Epilepsy is a neurological network disease with genetics playing a much greater role than
was previously appreciated. Unfortunately, the relationship between genetic basis and …

Objective Recent work has shown that people with common epilepsies have characteristic
patterns of cortical thinning, and that these changes may be progressive over time …

Objective MRI studies of genetic generalized epilepsies have mainly described group-level
changes between patients and healthy controls. To determine the endophenotypic potential …

Objective Juvenile myoclonic epilepsy (JME) is the most common genetic generalized
epilepsy syndrome. Myoclonus may relate to motor system hyperexcitability and can be …

Mesial temporal lobe epilepsy (mTLE) is the most common epilepsy syndrome which will
eventually become pharmacologically intractable partial-onset seizures. Regulation of gene …

Objective To examine the shared familial contribution to hippocampal and extrahippocampal
morphological abnormalities in patients with sporadic temporal lobe epilepsy (TLE) and their …

Background and purposes Brain morphometry is an important assessment technique to
assess certain morphological brain features of various brain regions, which can be …

Abnormal Temporal Lobe Morphology in Asymptomatic Relatives of Patients With
Hippocampal Sclerosis: A Replication Study Yaakub SN, Barker GJ, Carr SJ, et al. Epilepsia …

Evidence for a genetic effect in altered cortical surface area but not in cortical thinning in
siblings of patients with mesial temporal lobe epilepsy: Commentary on: "Abnormal temporal …