Synthesis and Biological Evaluation of New Schiff Bases Derived from 4-Amino-5-(3-fluorophenyl)-1, 2, 4-triazole-3-thione

S Janowska, D Khylyuk, M Janowski, U Kosikowska… - Molecules, 2023 - mdpi.com
The treatment of infectious diseases is a challenging issue faced by the medical community.
The emergence of drug-resistant strains of bacteria and fungi is a major concern …

Schiff-base ligands containing phenanthroline terminals: synthesis, characterization, biological activities and molecular docking study

G Uluçam, U Bagcı, AŞ Yılmaz, B Yentürk - Spectrochimica Acta Part A …, 2022 - Elsevier
Three new phenanthroline-derived ligands were synthesized by the Schiff base
condensation method. The first ligand was the result of 1, 10-phenanthroline-2 …

Structural characterization, theoretical and antibacterial study of a V-shaped, cyclohexane bridged ONNO Schiff base

NH Nasaruddin, SN Ahmad, SS Sirat, KW Tan… - Journal of Molecular …, 2022 - Elsevier
A tetradentate ONNO Schiff base bearing two chloro substituents, namely 6, 6′-((1E, 1′ E)-
(cyclohexane-1, 2-diylbis (azanylylidene)) bis (methanylylidene)) bis (2 …

Novel N-benzyl-2-oxo-1, 2-dihydrofuro [3, 4-d] pyrimidine-3 (4H)-carboxamide as anticancer agent: Synthesis, drug-likeness, ADMET profile, DFT and molecular …

AŞ Yılmaz, G Uluçam - Heliyon, 2023 - cell.com
A novel compound N-benzyl-2-oxo-1, 2-dihydrofuro [3, 4-d] pyrimidine-3 (4H)-carboxamide
(DHFP) was synthesized by addition, rearrangement, and intramolecular cyclization …

Antimicrobial activity, design, and synthesis of a novel trimethoprim derivative

BH Latief - Journal of the Indian Chemical Society, 2025 - Elsevier
The study aims to synthesize new derivatives of trimethoprim in two steps: the first step
contains synthesis of Schiff bases using (4-hydroxybenzaldehyde, Furfural, and …

DFT Calculation, ADME/T and Molecular Docking Approach of Methyl 2-oxo-1, 2-dihydrofuro [3, 4-d] pyrimidine-3 (4H) carboxylate

G Uluçam - Journal of the Mexican Chemical Society, 2024 - jmcs.org.mx
The optimized geometry of methyl 2-oxo-1, 2-dihydrofuro [3, 4-d] pyrimidine-3 (4H)
carboxylate (FP) was determined by density functional theory calculations. Geometric …