Immune response to Tick-Borne hemoparasites: Host adaptive immune response mechanisms as potential targets for therapies and vaccines
Tick-transmitted pathogens cause infectious diseases in both humans and animals. Different
types of adaptive immune mechanisms could be induced in hosts by these microorganisms …
types of adaptive immune mechanisms could be induced in hosts by these microorganisms …
Eimeria tenella rhoptry neck protein 2 plays a key role in the process of invading the host intestinal epithelium
Y Li, T Zhang, X Liu, T Pan, J Li, W Yang, X Cao… - Veterinary …, 2024 - Elsevier
The Apicomplexa parasitic phylum rhoptry neck protein 2 (RON2) plays a key role in the
process of invading host cells. Eimeria tenella, an intracellular protozoan shares a similar …
process of invading host cells. Eimeria tenella, an intracellular protozoan shares a similar …
The GP-45 Protein, a Highly Variable Antigen from Babesia bigemina, Contains Conserved B-Cell Epitopes in Geographically Distant Isolates
MA Mercado-Uriostegui, LA Castro-Sánchez… - Pathogens, 2022 - mdpi.com
In B. bigemina, the 45 kilodaltons glycoprotein (GP-45) is the most studied. GP-45 is
exposed on the surface of the B. bigemina merozoite, it is believed to play a role in the …
exposed on the surface of the B. bigemina merozoite, it is believed to play a role in the …
Evaluation of the humoral and mucosal immune response of a multiepitope vaccine against COVID-19 in pigs
J Mosqueda, DJ Hernandez-Silva… - Frontiers in …, 2023 - frontiersin.org
Introduction This study evaluated the immune response to a multiepitope recombinant
chimeric protein (CHIVAX) containing B-and T-cell epitopes of the SARS-CoV-2 spike's …
chimeric protein (CHIVAX) containing B-and T-cell epitopes of the SARS-CoV-2 spike's …
Spherical Body Protein 4 from Babesia bigemina: A Novel Gene That Contains Conserved B-Cell Epitopes and Induces Cross-Reactive Neutralizing Antibodies in …
Bovine babesiosis is a tick-transmitted disease caused by intraerythrocytic protozoan
parasites of the genus Babesia. Its main causative agents in the Americas are Babesia …
parasites of the genus Babesia. Its main causative agents in the Americas are Babesia …
A conserved protein of Babesia microti elicits partial protection against Babesia and Plasmodium infection
Y Wang, Q Zhang, W Zhang, J Chen, J Dai, X Zhou - Parasites & Vectors, 2023 - Springer
Abstract Background The protozoan parasite Babesia microti that causes the zoonotic
disease babesiosis resides in the erythrocytes of its mammalian host during its life-cycle. No …
disease babesiosis resides in the erythrocytes of its mammalian host during its life-cycle. No …
Babesia bovis RON2 binds to bovine erythrocytes through a highly conserved epitope
L Cuy-Chaparro, D Barney-Borrero… - Veterinary …, 2024 - Elsevier
B. bovis invasion of bovine erythrocytes requires tight junction formation involving AMA-
1/RON2 complex interaction. RON2 has been considered a vaccine candidate since …
1/RON2 complex interaction. RON2 has been considered a vaccine candidate since …
A prime-boost combination of a three-protein cocktail and multiepitopic MVA as a vaccine against Babesia bigemina elicits neutralizing antibodies and a Th1 cellular …
VN Montenegro, JM Jaramillo-Ortiz, MS Paoletta… - Ticks and Tick-borne …, 2022 - Elsevier
In the intraerythrocytic protozoan parasites of the genus Babesia both innate and adaptive
immune responses are necessary to confer protection against clinical disease. In particular …
immune responses are necessary to confer protection against clinical disease. In particular …
A Babesia microti conserved membrane-associated protein Bm8 elicits partial protection against Babesia and Plasmodium infection
Y Wang, Q Zhang, W Zhang, J Chen, J Dai, X Zhou - 2023 - researchsquare.com
The protozoan parasite Babesia microti that causes the zoonoses, babesiosis interacts with
the host erythrocytes during its life cycle. So far, no effective vaccines are available to …
the host erythrocytes during its life cycle. So far, no effective vaccines are available to …
Molecular Mechanisms of Babesia Invasion: Potential Targets for Vaccine Development
J Mosqueda, SM López… - … infective Research and …, 2020 - benthamdirect.com
Babesia bovis and Babesia bigemina are protozoan parasites of the Apicomplexa phylum
that cause bovine babesiosis, a cattle disease transmitted by ticks of the Rhipicephalus …
that cause bovine babesiosis, a cattle disease transmitted by ticks of the Rhipicephalus …