Functions of 'A disintegrin and metalloproteases (ADAMs)'in the mammalian nervous system

HE Hsia, J Tüshaus, T Brummer, Y Zheng… - Cellular and Molecular …, 2019 - Springer
Abstract 'A disintegrin and metalloproteases'(ADAMs) are a family of transmembrane
proteins with diverse functions in multicellular organisms. About half of the ADAMs are active …

Proteases in brain tumour progression

N Levičar, RK Nutall, TT Lah - Acta neurochirurgica, 2003 - Springer
Summary¶ Local invasion of tumour cells is characteristic of brain tumour progression. It is
associated with increased motility and a potential to hydrolyse macromolecular components …

Potential role for ADAM15 in pathological neovascularization in mice

K Horiuchi, G Weskamp, L Lum… - … and cellular biology, 2003 - Taylor & Francis
ADAM15 (named for a disintegrin and metalloprotease 15, metargidin) is a membrane-
anchored glycoprotein that has been implicated in cell-cell or cell-matrix interactions and in …

The ADAMs family: coordinators of nervous system development, plasticity and repair

P Yang, KA Baker, T Hagg - Progress in neurobiology, 2006 - Elsevier
A disintegrin and metalloprotease (ADAM) transmembrane proteins have metalloprotease,
integrin-binding, intracellular signaling and cell adhesion activities. In contrast to other …

Molecular mechanisms of cellular interactions in peripheral nerve regeneration

P Küry, G Stoll, HW Müller - Current opinion in neurology, 2001 - journals.lww.com
The peripheral nervous system, as opposed to the central nervous system, has the intrinsic
capacity to regenerate. It was recognized long ago that this can be achieved only after an …

Comparative localization of ADAMs 10 and 15 in human cerebral cortex normal aging, Alzheimer disease and Down syndrome

HG Bernstein, A Bukowska, D Krell, B Bogerts… - Journal of …, 2003 - Springer
Using immunohistochemical techniques we studied the light microscopic localization of
ADAMs (A Disintegrin And Metalloprotease) 10 and 15 in different neocortical areas of the …

Differential gene expression in white and brown preadipocytes

S Boeuf, M Klingenspor, NLW van Hal… - Physiological …, 2001 - journals.physiology.org
White (WAT) and brown (BAT) adipose tissue are tissues of energy storage and energy
dissipation, respectively. Experimental evidence suggests that brown and white …

ADAM proteins in the brain

U Novak - Journal of Clinical Neuroscience, 2004 - Elsevier
ADAM proteins are a family of metalloproteinases with a disintegrin domain. They have
proteolytic as well as adhesive functions and can be involved in cell fusion events. Some …

ADAM15 decreases integrin αvβ3/vitronectin-mediated ovarian cancer cell adhesion and motility in an RGD-dependent fashion

V Beck, H Herold, A Benge, B Luber, P Hutzler… - The international journal …, 2005 - Elsevier
We have recently described that integrin αvβ3 upon interaction with its major extracellular
matrix ligand vitronectin induces adhesion, motility, and proliferation of human ovarian …

ADAM23 is a cell‐surface glycoprotein expressed by central nervous system neurons

AP Goldsmith, SJ Gossage… - Journal of …, 2004 - Wiley Online Library
Several members of the ADAM (a disintegrin and metalloprotease) family of proteins have
been implicated in biological processes ranging from fertilization to myoblast fusion and …