This review aims to survey the current state of mechanotransduction in vascular smooth
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …

Cellular mechanotransduction, a critical regulator of numerous biological processes, is the
conversion from mechanical signals to biochemical signals regarding cell activities and …

The endothelium can evoke relaxations of the underlying vascular smooth muscle, by
releasing vasodilator substances. The best‐characterized endothelium‐derived relaxing …

Efficient delivery of therapeutics across the neuroprotective blood–brain barrier (BBB)
remains a formidable challenge for central nervous system drug development. High‐fidelity …

Mechanotransduction, the conversion of physical forces into biochemical signals, is
essential for various physiological processes such as the conscious sensations of touch and …

Although the shapes of organisms are encoded in their genome, the developmental
processes that lead to the final form of vertebrates involve a constant feedback between …

Haemodynamic forces influence the functional properties of vascular endothelium.
Endothelial cells (ECs) have a variety of receptors, which sense flow and transmit …

Development of an in vitro living cell-based model of the intestine that mimics the
mechanical, structural, absorptive, transport and pathophysiological properties of the human …

Primary cilia are solitary, generally non-motile, hair-like protrusions that extend from the
surface of cells between cell divisions. Their antenna-like structure leads naturally to the …

Endothelial dysfunction is now considered an important early event in the development of
atherosclerosis, which precedes gross morphological signs and clinical symptoms. The …