Cyclic nucleotide-gated (CNG) channels are nonselective cation channels first identified in
retinal photoreceptors and olfactory sensory neurons (OSNs). They are opened by the direct …

▪ Abstract The olfactory system sits at the interface of the environment and the nervous
system and is responsible for correctly coding sensory information from thousands of …

Retinitis Pigmentosa (RP) reflects a range of inherited retinal disorders which involve
photoreceptor degeneration and retinal pigmented epithelium dysfunction. Despite the …

Cyclic nucleotide–gated (CNG) channels are key to the signal transduction machinery of
certain sensory modalities both in vertebrate and invertebrate organisms. They translate a …

Patterns of neuronal excitation in complex populations can be mapped anatomically by
activating ionotropic glutamate receptors in the presence of 1‐amino‐4‐guanidobutane …

This paper shows that the selectivity properties of monovalent cation channels found in
biological membranes can originate simply from geometrical properties of the inner core of …

Purpose: In the rd/rd mouse, the cell death of rod photoreceptors has been correlated to
abnormal levels of the cyclic nucleotide cGMP within photoreceptors. Given that cGMP is …

This review summarizes current knowledge of the hair cell mechanotransducer channel, the
ion channel responsible for detecting mechanical stimuli in the inner ear and one of the few …

The slow vacuolar (SV) channel can mediate a large part of the ionic current in plant
tonoplasts, but its actual physiological role is still unclear. We demonstrate that in vacuoles …

There has been rapid progress in understanding the structural basis of ion selectivity and
permeation in both ligand-and voltage-gated channels. Recognition of similarities in overall …