Chiral indole derivatives such as indolines and indolenines are important heterocyclic
frameworks which constitute the core structures of many natural products and bioactive …

This Review summarizes the development of catalytic asymmetric dearomatization (CADA)
reactions. The CADA reactions discussed herein include oxidative dearomatization …

The asymmetric organocatalysis is definitely one of the most powerful and versatile tools for
the rapid construction of various spirocyclic oxindoles. In the past few years, a number of …

Abstract 140 Years ago Adolf von Baeyer proposed the structure of a heteroaromatic
compound which revolutionized organic and medical chemistry: indole. After more than a …

The stereocontrolled construction of chiral carbo-and heterocycles is a topic of paramount
importance in modern organic synthesis, driven by the predominance of chiral mono-and …

In general, DA reactions can be classified into two types of suprafacial [π4s+ π2s]
cycloadditions:(i) the normal and (ii) inverse-electron-demand DA reactions (Scheme 1) …

Heterocyclic structural architectures occur in many bioactive natural products and synthetic
drugs, and these structural units serve as important intermediates in organic synthesis. This …

Over the years, alkaloids derived from indole dearomatization, such as indolenine and
indolines have been evolved as promising therapeutic agents due to their important …

Enantioenriched indole derivatives are widely found in natural products, pharmaceuticals
and bioactive compounds. Therefore, developing efficient methods for the synthesis of …

Carbazolespirooxindole derivatives were synthesized in a high-yielding, atypically rapid,
stereocontrolled Diels–Alder reaction catalyzed by a C 2-symmetric bisthiourea …