Nucleic acid drugs have the advantages of rich target selection, simple in design, good and
enduring effect. They have been demonstrated to have irreplaceable superiority in brain …

Background Over the past 30 years, brain tumors have been intensively studied with a
variety of therapeutic approaches. However, brain cancer is still one of the most lethal forms …

Cancer stem cells (CSCs) possess the ability to indefinitely proliferate and resist therapy,
leading to cancer relapse and metastasis. To address this, we aimed to develop a CSC …

Despite the impressive strides in the research community, numerous obstacles pose marked
challenges in the treatment of central nervous system (CNS) disorders. The limitations of …

Nucleic acid-based drugs are changing the scope of emerging medicine in preventing and
treating diseases. Nanoparticle systems based on lipids and polymers developed to …

Traditional Chinese medicine (TCM) has been employed for centuries in treating and
managing Alzheimer's disease (AD). However, their effective delivery to target sites can be a …

Dendritic cells (DCs), a kind of specialized immune cells, play key roles in antitumor immune
response and promotion of innate and adaptive immune responses. Recently, many …

Glioblastoma multiforme is a very combative and threatening type of cancer. The standard
course of treatment involves excising the tumor surgically, then administering chemotherapy …