Currently Used Methods to Evaluate the Efficacy of Therapeutic Drugs and Kidney Safety

HJ Huang, CL Chou, TT Sandar, WC Liu, HC Yang… - Biomolecules, 2023 - mdpi.com
Kidney diseases with kidney failure or damage, such as chronic kidney disease (CKD) and
acute kidney injury (AKI), are common clinical problems worldwide and have rapidly …

Urinary biomarkers for amyotrophic lateral sclerosis: candidates, opportunities and considerations

ML Rogers, DW Schultz, V Karnaros… - Brain …, 2023 - academic.oup.com
Amyotrophic lateral sclerosis is a relentless neurodegenerative disease that is mostly fatal
within 3–5 years and is diagnosed on evidence of progressive upper and lower motor …

Identification of a new RNA and protein integrated biomarker panel associated with kidney function impairment in DKD: translational implications

A Scamporrino, S Di Mauro, A Filippello… - International Journal of …, 2023 - mdpi.com
Diabetic kidney disease (DKD) is a complication that strongly increases the risk of end-stage
kidney disease and cardiovascular events. The identification of novel, highly sensitive, and …

Association between Albumin Alterations and Renal Function in Patients with Type 2 Diabetes Mellitus

M Nugnes, M Baldassarre, D Ribichini… - International Journal of …, 2024 - mdpi.com
Diabetic kidney disease (DKD) is a major cause of morbidity and mortality in individuals with
type 2 diabetes mellitus (T2DM). The aim of this study was to investigate whether albumin …

Disease specific urinary biomarkers in the central nervous system

M Duggins-Warf, A Ghalali, J Sesen, T Martinez… - Scientific Reports, 2023 - nature.com
Urinary biomarkers can diagnose and monitor pathophysiologic conditions in the central
nervous system (CNS). However, focus is often on single diseases, with limited data on …

Urinary growth differentiation factor 15 predicts renal function decline in diabetic kidney disease

T Oshita, S Watanabe, T Toyohara, R Kujirai… - Scientific reports, 2023 - nature.com
Sensitive biomarkers can enhance the diagnosis, prognosis, and surveillance of chronic
kidney disease (CKD), such as diabetic kidney disease (DKD). Plasma growth differentiation …

Usefulness of urinary tubule injury markers for predicting progression of renal dysfunction in patients with type 2 diabetes and albuminuria: The Fukuoka Diabetes …

H Ide, M Iwase, T Ohkuma, H Fujii, Y Komorita… - Diabetes Research and …, 2022 - Elsevier
Aims We prospectively investigated the association of urinary tubule injury markers with
estimated glomerular filtration rate (eGFR) decline in Japanese patients with type 2 …

Measurement of Urinary Gc-Globulin by a Fluorescence ELISA Technique: Method Validation and Clinical Evaluation in Septic Patients—A Pilot Study

T Kőszegi, Z Horváth-Szalai, D Ragán, B Kósa… - Molecules, 2023 - mdpi.com
A major complication of sepsis is the development of acute kidney injury (AKI). In case of
acute tubular damage, Gc-globulin, a known serum sepsis marker is increasingly filtrated …

Potential application of Klotho as a prognostic biomarker for patients with diabetic kidney disease: a meta-analysis of clinical studies

LX Yu, MY Sha, Y Chen, F Tan, X Liu… - … Advances in Chronic …, 2023 - journals.sagepub.com
Background: Diabetic kidney disease (DKD) is a serious diabetic complication and the
performance of serum Klotho in DKD's prognostic evaluation is controversial. Objective: To …

[HTML][HTML] Artemether attenuates renal tubular injury by regulating iron metabolism in mice with streptozotocin-induced diabetes

G Rong, Y Cai, W Weng, Y Chen, X Yu… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Objectives: Renal tubular injury plays an important role in the progression of diabetic kidney
disease. Previous studies demonstrated that artemether, an antimalarial agent, exerts renal …