Antiretrovirals for reducing the risk of mother‐to‐child transmission of HIV infection

N Siegfried, L van der Merwe… - … of systematic reviews, 2011 - cochranelibrary.com
Background Antiretroviral drugs reduce viral replication and can reduce mother‐to‐child
transmission of HIV either by lowering plasma viral load in pregnant women or through post …

Secondary immunodeficiencies, including HIV infection

J Chinen, WT Shearer - Journal of Allergy and Clinical Immunology, 2010 - Elsevier
Extrinsic factors can adversely affect immune responses, producing states of secondary
immunodeficiency and consequent increased risk of infections. These immunodeficiencies …

HIV-1 subtype C-infected individuals maintaining high viral load as potential targets for the “test-and-treat” approach to reduce HIV transmission

V Novitsky, R Wang, H Bussmann, S Lockman… - PLoS …, 2010 - journals.plos.org
The first aim of the study is to assess the distribution of HIV-1 RNA levels in subtype C
infection. Among 4,348 drug-naïve HIV-positive individuals participating in clinical studies in …

HIV‐free survival at 12–24 months in breastfed infants of HIV‐infected women on antiretroviral treatment

LC Chikhungu, S Bispo, N Rollins… - Tropical Medicine & …, 2016 - Wiley Online Library
Objective To provide estimates of HIV‐free survival at 12–24 months in breastfed children by
maternal ART (6 months or lifelong) to inform WHO HIV and Infant Feeding guidelines …

[HTML][HTML] Maternal risk factors for HIV infection in infants in northeastern Brazil

LMD De Lemos, J Lippi, GW Rutherford… - International Journal of …, 2013 - Elsevier
Introduction While the rate of vertically transmitted HIV infection has fallen in most regions of
Brazil, there have been no similar decreases in northern and northeastern Brazil. Objective …

Human immunodeficiency virus type 1 mother‐to‐child transmission and prevention: successes and controversies

M Cavarelli, G Scarlatti - Journal of internal medicine, 2011 - Wiley Online Library
Cavarelli M., Scarlatti G (Unit of Viral Evolution and Transmission, DITID, San Raffaele
Scientific Institute). Human immunodeficiency virus type 1 mother‐to‐child transmission and …

Th1 cytokine gene polymorphism and the corresponding plasma cytokine levels: A comparative study in HIV‐1 positive and exposed uninfected infants

VR Chavan, S Ahir, S Kerkar, Z Ansari… - Journal of Medical …, 2022 - Wiley Online Library
Abstract The pro‐inflammatory (Th1) cytokines namely interleukin (IL)‐2, IL‐6, IL‐12,
interferon (IFN)‐γ, tumor necrosis factor‐α (TNF‐α) are vital in the clearance of HIV infection …

HIV-1 Disease Progression Is Associated with Bile-Salt Stimulated Lipase (BSSL) Gene Polymorphism

MJ Stax, NA Kootstra, AB van't Wout, MWT Tanck… - PLoS …, 2012 - journals.plos.org
Background DC-SIGN expressed by dendritic cells captures HIV-1 resulting in trans-
infection of CD4+ T-lymphocytes. However, BSSL (bile-salt stimulated lipase) binding to DC …

Dynamics of breast milk HIV-1 RNA with unilateral mastitis or abscess

K Semrau, L Kuhn, DR Brooks, H Cabral… - JAIDS Journal of …, 2013 - journals.lww.com
Background: Mastitis and abscess in HIV-infected women increase the risk of breastfeeding
transmission of HIV. Guidelines encourage women to stop breastfeeding on the affected …

Antiretroviral treatment, viral load of mothers & perinatal HIV transmission in Mumbai, India

SP Ahir, V Chavan, S Kerkar… - Indian Journal of …, 2013 - journals.lww.com
Methods: A total of 58 HIV positive women were enrolled at the time of delivery and their
plasma samples were obtained within 24 h of delivery for estimation of viral load. Viral load …