Microbial natural compounds and secondary metabolites as Immunomodulators: A review

F Mahmoudi, MHT Jalayeri, A Montaseri… - International Journal of …, 2024 - Elsevier
Immunomodulatory therapies are beneficial strategies for the improvement of immune
system function. Today, due to the increasing prevalence of immune disorders, cancer, and …

Cyclosporine A Delivery Platform for Veterinary Ophthalmology—A New Concept for Advanced Ophthalmology

M Padjasek, B Qasem, A Cisło-Pakuluk, K Marycz - Biomolecules, 2022 - mdpi.com
Cyclosporine A (CsA) is a selective and reversible immunosuppressant agent that is widely
used as a medication for a wide spectrum of diseases in humans such as graft versus host …

Electrospun PVP-core/PHBV-shell fibers to eliminate tailing off for an improved sustained release of curcumin

Y Liu, X Chen, DG Yu, H Liu, Y Liu… - Molecular …, 2021 - ACS Publications
Tailing off release in the sustained release of water-insoluble curcumin (Cur) is a significant
challenge in the drug delivery system. As a novel solution, core–shell nanodrug containers …

A hybrid ocular delivery system of cyclosporine-A comprising nanomicelle-laden polymeric inserts with improved efficacy and tolerability

E Terreni, P Chetoni, S Burgalassi, S Tampucci… - Biomaterials …, 2021 - pubs.rsc.org
We report on hybrid nanomicelle–polymer inserts for improved delivery of cyclosporine A
(CyA) to the surface of the eye. Hybrid inserts containing a nanomicellar formulation were …

Development of a mucilage coating including nanoencapsulated essential oils for extending shelf life of button mushrooms (Agaricus bisporus)

AM Faraj, M Nouri - Food Packaging and Shelf Life, 2024 - Elsevier
The shelf life of mushrooms is limited, which prevents distribution and marketing as a fresh
product. The aim of present research is to coat Agaricus bisporus mushroom by chia seed …

[HTML][HTML] Linoleic acid-based transferosomes for topical ocular delivery of cyclosporine A

O Uwaezuoke, LC Du Toit, P Kumar, N Ally… - Pharmaceutics, 2022 - mdpi.com
Delivering high-molecular-weight hydrophobic peptides, such as cyclosporine A, across the
corneal epithelium remains a challenge that is complicated by other physio-anatomical …

Amorphous solid dispersions of cyclosporine A with improved bioavailability prepared via hot melt extrusion: Formulation, physicochemical characterization, and in …

X Jiang, Y Zhao, Q Guan, S Xiao, W Dong… - European Journal of …, 2022 - Elsevier
In this study, the amorphous solid dispersions of cyclosporine A (CsA-ASDs) were prepared
by hot melt extrusion (HME) with PVP K12 as carrier to improve the oral bioavailability of …

Fabricating polymer/surfactant/cyclodextrin hybrid particles for possible nose-to-brain delivery of ropinirole hydrochloride: In vitro and ex vivo evaluation

EM Saitani, N Pippa, DR Perinelli, A Forys… - International journal of …, 2024 - mdpi.com
Ropinirole is a non-ergolinic dopamine agonist used to manage Parkinson's disease and it
is characterized by poor oral bioavailability. This study aimed to design and develop …

Electrospun Nanofibers: Shaping the Future of Controlled and Responsive Drug Delivery

M Wildy, P Lu - Materials, 2023 - mdpi.com
Electrospun nanofibers for drug delivery systems (DDS) introduce a revolutionary means of
administering pharmaceuticals, holding promise for both improved drug efficacy and …

Development, characterization, and burn wound-healing potential of neomycin-loaded clay-reinforced nanofibers

BS Alotaibi, AK Khan, M Ijaz, H Yasin, S Nawazish… - ACS …, 2023 - ACS Publications
Background: Skin wounds affect millions of individuals around the world, and their treatment
is expensive. Objective: The purpose of this study was to make neomycin-loaded …