Cholangiocarcinoma (CCA) includes a cluster of highly heterogeneous biliary malignant
tumours that can arise at any point of the biliary tree. Their incidence is increasing globally …

Cholangiocarcinoma is a disease entity comprising diverse epithelial tumours with features
of cholangiocyte differentiation: cholangiocarcinomas are categorized according to …

Single-cell multi-omics (scMulti-omics) allows the quantification of multiple modalities
simultaneously to capture the intricacy of complex molecular mechanisms and cellular …

The neuroendocrine carcinoma of the gastrointestinal system (GIS-NEC) is a rare but highly
malignant neoplasm. We analyzed 115 cases using whole-genome/exome sequencing …

One of the most important points in the meta-analyses is certainly represented by the
assessment of the quality of the studies included in such research. The meta-analyses are …

The epithelial–mesenchymal transition (EMT) is one of the processes by which epithelial
cells transdifferentiate into mesenchymal cells in the developmental stage, known as …

We have described multipotent progenitor-like cells within the major pancreatic ducts
(MPDs) of the human pancreas. They express PDX1, its surrogate surface marker P2RY1 …

Liver cancer is the second most common cause of cancer-related death. The major forms of
primary liver cancer are hepatocellular carcinoma (HCC) and intrahepatic …

Ampullary carcinomas (ACs) represent a rare entity, accounting for approximately 0.2% of all
gastrointestinal solid tumors and 20% of all periampullary cancers (PACs). Unfortunately …

Pancreatic Ductal Adenocarcinoma (PDAC) is the fourth most common cause of cancer-
related death and is the most lethal of common malignancies with a five-year survival rate …