[HTML][HTML] New viral vectors for infectious diseases and cancer

E Sasso, AM D'Alise, N Zambrano, E Scarselli… - Seminars in …, 2020 - Elsevier
Since the discovery in 1796 by Edward Jenner of vaccinia virus as a way to prevent and
finally eradicate smallpox, the concept of using a virus to fight another virus has evolved into …

Cell-cell fusion mediated by viruses and HERV-derived fusogens in cancer initiation and progression

T Dittmar, J Weiler, T Luo, R Hass - Cancers, 2021 - mdpi.com
Simple Summary Even though it is known that (cancer) cells can fuse, it is still less
understood how (cancer) cells merge their plasma membranes, thereby giving rise to bi-and …

Oncolytic virotherapy in solid tumors: the challenges and achievements

KT Jin, WL Du, YY Liu, HR Lan, JX Si, XZ Mou - Cancers, 2021 - mdpi.com
Simple Summary Oncolytic virotherapy (OVT) is a promising approach in cancer
immunotherapy. Oncolytic viruses (OVs) could be applied in cancer immunotherapy without …

Herpes simplex virus oncolytic immunovirotherapy: The blossoming branch of multimodal therapy

L Menotti, E Avitabile - International journal of molecular sciences, 2020 - mdpi.com
Oncolytic viruses are smart therapeutics against cancer due to their potential to replicate and
produce the needed therapeutic dose in the tumor, and to their ability to self-exhaust upon …

Oncolytic viral vectors in the era of diversified cancer therapy: From preclinical to clinical

C Tang, L Li, T Mo, J Na, Z Qian, D Fan, X Sun… - Clinical and …, 2022 - Springer
With the in-depth research and wide application of immunotherapy recently, new therapies
based on oncolytic viruses are expected to create new prospects for cancer treatment via …

Clinical Advances and Future Directions of Oncolytic Virotherapy for Head and Neck Cancer

Z Wang, P Sun, Z Li, S Xiao - Cancers, 2023 - mdpi.com
Simple Summary Head and neck cancer (HNC) is a significant global health issue, and
traditional treatments such as surgery, chemotherapy, and radiation therapy often have …

Efficient delivery and replication of oncolytic virus for successful treatment of head and neck cancer

M Hamada, Y Yura - International Journal of molecular sciences, 2020 - mdpi.com
Head and neck cancer has been treated by a combination of surgery, radiation, and
chemotherapy. In recent years, the development of immune checkpoint inhibitors (ICIs) has …

Extracellular events involved in cancer cell–cell fusion

T Dittmar, R Hass - International Journal of Molecular Sciences, 2022 - mdpi.com
Fusion among different cell populations represents a rare process that is mediated by both
intrinsic and extracellular events. Cellular hybrid formation is relayed by orchestrating tightly …

Cell fusion and syncytium formation in betaherpesvirus infection

J Tang, G Frascaroli, X Zhou, J Knickmann, W Brune - Viruses, 2021 - mdpi.com
Cell–cell fusion is a fundamental and complex process that occurs during reproduction,
organ and tissue growth, cancer metastasis, immune response, and infection. All enveloped …

The antitumor effect of oncolytic respiratory syncytial virus via the tumor necrosis factor-alpha induction and ROS-bax-mediated mechanisms

M Samadi, T Mokhtari-Azad, A Nejati, Z Norooz-Babaei… - BMC cancer, 2023 - Springer
Background Cervical cancer represents one of the most prevalent cancers among women
worldwide, particularly in low-and middle-income nations. Oncolytic viruses (OVs) can infect …