Age-related macular degeneration (AMD) is a complex, multifactorial and progressive retinal
disease affecting millions of people worldwide. In developed countries, it is the leading …

Glucocorticoids (GCs) are essential steroid hormones that regulate numerous metabolic and
homeostatic functions in almost all physiological systems. Synthetic glucocorticoids are …

Eye diseases are associated with visual impairment, reduced quality of life, and may even
lead to vision loss. The efficacy of available treatment of eye diseases is not satisfactory. The …

Bacterial keratitis is a serious bacterial infection of the cornea that can cause sight loss in
severe cases because of the sharp decline of efficacious antibiotics. Herein, a targeted …

Dry eye formation often originates from oxidative damage to the ocular surface, which can
be caused by external environment or internal pathologic factors. Esculetin (6, 7 …

Dry eye and tear dysfunction are common ocular disorders that cause cornea barrier
disruption resulting in a poorly lubricated and irregular cornea epithelium, eye irritation and …

Neovascularization during ocular tissue repair can cause severe visual loss in the optical
axis and is therefore an issue of considerable concern to ophthalmologists. Here, we …

Alkali burn (AB) is one of the most serious ocular traumas in the world, characterized by
extreme ocular surface disorders, critical secondary dry eye and irreversible vision loss. The …

Aim Chemical injuries can potentially lead to the necrosis anterior segment of the eye, and
cornea in particular. Inflammatory cytokines are the first factors produced after chemical …

(1) Background: Abnormal corneal wound healing compromises visual acuity and can lead
to neuropathic pain. Conventional treatments usually fail to restore the injured corneal …