Nano spray drying for encapsulation of pharmaceuticals

C Arpagaus, A Collenberg, D Rütti, E Assadpour… - International journal of …, 2018 - Elsevier
Many pharmaceuticals such as pills, capsules, or tablets are prepared in a dried and
powdered form. In this field, spray drying plays a critical role to convert liquid pharmaceutical …

[PDF][PDF] Pharmaceutical particle engineering via nano spray drying—Process parameters and application examples on the laboratory-scale

C Arpagaus - Int. J. Med. Nano Res, 2018 - pdfs.semanticscholar.org
Spray drying plays a crucial role in the processing of pharmaceutical products such as pills,
capsules, and tablets as it is used to convert drug-containing liquids into dried powdered …

Development of a new inhaler for high-efficiency dispersion of spray-dried powders using computational fluid dynamics (CFD) modeling

W Longest, D Farkas - The AAPS journal, 2019 - Springer
Computational fluid dynamics (CFD) modeling offers a powerful tool for the development of
drug delivery devices using a first principles approach but has been underutilized in the …

[HTML][HTML] Administration of dry powders during respiratory supports

WR Ke, RYK Chang, PCL Kwok, P Tang… - Annals of …, 2021 - ncbi.nlm.nih.gov
Inhaled drugs are routinely used for the treatment of respiratory-supported patients. To date,
pressurized metered dose inhalers and nebulizers are the two platforms routinely employed …

Use of computational fluid dynamics (CFD) dispersion parameters in the development of a new DPI actuated with low air volumes

W Longest, D Farkas, K Bass, M Hindle - Pharmaceutical research, 2019 - Springer
Purpose To determine the predictive power of computational fluid dynamics (CFD)-based
dispersion parameters in the development of a new inline DPI that is actuated with low …

Efficient nose-to-lung (N2L) aerosol delivery with a dry powder inhaler

PW Longest, L Golshahi, SRB Behara… - Journal of Aerosol …, 2015 - liebertpub.com
Purpose: Delivering aerosols to the lungs through the nasal route has a number of
advantages, but its use has been limited by high depositional loss in the extrathoracic …

Development of an inline dry powder inhaler that requires low air volume

D Farkas, M Hindle, PW Longest - Journal of Aerosol Medicine and …, 2018 - liebertpub.com
Background: Inline dry powder inhalers (DPIs) are actuated by an external air source and
have distinct advantages for delivering aerosols to infants and children, and to individuals …

Development of an inline dry powder inhaler for oral or trans-nasal aerosol administration to children

D Farkas, M Hindle, S Bonasera, K Bass… - Journal of aerosol …, 2020 - liebertpub.com
Background: Dry powder inhalers (DPIs) offer a number of advantages, such as rapid
delivery of high-dose inhaled medications; however, DPI use in children is often avoided …

Development of dry powder inhaler patient interfaces for improved aerosol delivery to children

K Bass, W Longest - AAPS PharmSciTech, 2020 - Springer
The objective of this study was to explore different internal flow passages in the patient
interface region of a new air-jet–based dry powder inhaler (DPI) in order to minimize device …

Advancement of a positive-pressure dry powder inhaler for children: use of a vertical aerosolization chamber and three-dimensional rod array interface

D Farkas, S Bonasera, K Bass, M Hindle… - Pharmaceutical …, 2020 - Springer
Purpose Available dry powder inhalers (DPIs) have very poor lung delivery efficiencies in
children. The objective of this study was to advance and experimentally test a positive …