Background Despite advances in early detection and therapies, cancer is still one of the
most common causes of death worldwide. Since each tumor is unique, there is a need to …

Lung cancer is the leading cause of cancer-related deaths in North America and other
developed countries. One of the reasons lung cancer is at the top of the list is that it is often …

Cell-free DNA (cfDNA) is a widely used noninvasive biomarker for diagnosis and prognosis
of multiple disease states. Emerging evidence suggests that cfDNA might not just be passive …

Senescence refers to a cellular state featuring a stable cell‐cycle arrest triggered in
response to stress. This response also involves other distinct morphological and intracellular …

Liquid biopsy with circulating tumor DNA (ctDNA) profiling by next-generation sequencing
holds great promise to revolutionize clinical oncology. It relies on the basis that ctDNA …

Research and clinical use of circulating cell-free DNA (cirDNA) is expanding rapidly;
however, there remain large gaps in our understanding of the influence of lifestyle and …

The outbreak of COVID-19 has positively impacted the NGS market recently. Targeted
sequencing (TS) has become an important routine technique in both clinical and research …

Circulating cell-free DNA (cfDNA) is rapidly transitioning from discovery research to an
important tool in clinical decision making. However, the lack of harmonization of preanalytic …

Cell-free DNA (cfDNA) has become widely recognized as a promising candidate biomarker
for minimally invasive characterization of various genomic disorders and other clinical …

Neurological disorders such as stroke, multiple sclerosis, as well as the neurodegenerative
diseases Parkinson's or Alzheimer's disease are accompanied or even powered by danger …