Alzheimer disease (AD) is characterized by wide heterogeneity in cognitive and behavioural
syndromes, risk factors and pathophysiological mechanisms. Addressing this phenotypic …

Introduction Precision medicine methodologies and approaches have advanced our
understanding of the clinical presentation, development, progression, and management of …

Importance Sex differences in dementia risk are unclear, but some studies have found
greater risk for women. Objective To determine associations between sex and cognitive …

Introduction The overall goal of the Alzheimer's Disease Neuroimaging Initiative (ADNI) is to
validate biomarkers for Alzheimer's disease (AD) clinical trials. ADNI is a multisite …

Preventing or delaying Alzheimer disease (AD) through lifestyle interventions will come from
a better understanding of the mechanistic underpinnings of (1) why a significant proportion …

After advanced age, female sex is the major risk factor for late-onset Alzheimer's disease
(AD), the most common cause of dementia affecting over 24 million people worldwide. The …

Women represent ⅔ of the cases of Alzheimer's disease (AD). Current research has focused
on differential risks to explain higher rates of AD in women. However, factors that reduce risk …

Published epidemiological studies of traumatic brain injury (TBI) of all severities consistently
report higher incidence in men. Recent increases in the participation of women in sports and …

Sex or gender differences in the risk of Alzheimer's disease and related dementias (ADRD)
differ by world region, suggesting that there are potentially modifiable risk factors for …

Studies have shown that women on the Alzheimer's disease (AD) continuum have more
pathological tau in the brain and cerebrospinal fluid (CSF), than men. Some studies have …