Targeting macrophages as a therapeutic option in coronavirus disease 2019

M Gracia-Hernandez, EM Sotomayor… - Frontiers in …, 2020 - frontiersin.org
Immune cells of the monocyte/macrophage lineage are characterized by their diversity,
plasticity, and variety of functions. Among them, macrophages play a central role in antiviral …

Mantle cell lymphoma: a clinically heterogeneous disease in need of tailored approaches

BD Shah, P Martin, EM Sotomayor - Cancer Control, 2012 - journals.sagepub.com
Background Mantle cell lymphoma (MCL) remains incurable using conventional
chemotherapeutic approaches. New clinical data show that some patients have a …

Targeting HDAC6 improves anti-CD47 immunotherapy

M Gracia-Hernandez, AS Yende, N Gajendran… - Journal of Experimental …, 2024 - Springer
Background Cancer cells can overexpress CD47, an innate immune checkpoint that
prevents phagocytosis upon interaction with signal regulatory protein alpha (SIRPα) …

Genetic and environmental determinants in multiple myeloma: Implications for therapy

KH Shain, WS Dalton - … Cancers: From Molecular Pathobiology to Targeted …, 2012 - Springer
Multiple myeloma is an incurable hematopoietic malignancy linked to more than 10,000
deaths annually. This dyscrasia is associated with significant co-morbidities as a result of the …

Molecular Biology of Mantle Cell Lymphoma

B Shah, P Martin, J Tao, EM Sotomayor - Hematologic Cancers: From …, 2012 - Springer
Mantle cell lymphoma (MCL) is an aggressive Non-Hodgkin's lymphoma with nearly uniform
tendency for recurrence and untimely demise despite intensive chemotherapeutic …