Abstract The TFOS DEWS II Pathophysiology Subcommittee reviewed the mechanisms
involved in the initiation and perpetuation of dry eye disease. Its central mechanism is …

Corneal nerves are key components of the physiological system that controls ocular surface
homeostasis. The cornea is primarily innervated by the ophthalmic branch of the trigeminal …

Dry eye disease is a multifactorial disorder of the tears and ocular surface characterized by
symptoms of dryness and irritation. Although the pathogenesis of dry eye disease is not fully …

The 2017 consensus report of the Asia Dry Eye Society (ADES) on the definition and
diagnosis of dry eyes described dry eye disease as “Dry eye is a multifactorial disease …

The diagnosis of dry eye and its treatment has long been approached somewhat
subjectively. Even more so, it's an ocular ailment that hasn't always been treated with …

Goblet cells within the conjunctival epithelium are specialized cells that secrete mucins onto
the surface of the eye. Recent research has demonstrated new characteristics of the cells …

Dry eye is a common ocular surface inflammatory disease that significantly affects quality of
life. Dysfunction of the lacrimal function unit (LFU) alters tear composition and breaks ocular …

Dry eye disease (DED) is a multifactorial disease of the ocular surface and tear film that has
gained awareness as a public health problem. Characteristics of DED include tear film …

Purpose To provide a consensus clinical guideline for management of dry eye disease
associated with Sjögren disease by evaluating published treatments and recommending …

Keratoconjunctivitis sicca, or dry eye, is a common ocular disease prompting millions of
individuals to seek ophthalmological care. Regardless of the underlying etiology, dry eye …