Porous Si exhibits a number of properties that make it an attractive material for controlled
drug delivery applications: The electrochemical synthesis allows construction of tailored …

Introduction: Silica materials, in particular mesoporous silicas, have demonstrated excellent
properties to enhance the oral bioavailability of poorly water-soluble drugs. Current research …

Micro-and nano-mesoporous silicate particles are considered potential drug delivery
systems because of their ordered pore structures, large surface areas and the ease with …

Porous silicon (PSi) particles have been studied for the effects they elicit in Caco-2 and RAW
264.7 macrophage cells in terms of toxicity, oxidative stress, and inflammatory response …

Utilization of inorganic mesoporous materials in formulations of poorly water-soluble drugs
to enhance their dissolution and permeation behavior is a rapidly growing area in …

The research on porous silicon (PSi) materials for biomedical applications has expanded
greatly since the early studies of Leigh Canham more than 25 years ago. Currently, PSi …

ABSTRACT A poorly soluble model drug, indomethacin (IMC), was loaded into two types of
silica particles using three different loading methods. The loading efficiency and the …

Mesoporous materials have an ability to enhance dissolution properties of poorly soluble
drugs. In this study, different mesoporous silicon (thermally oxidized and thermally …

Mesoporous silicon (PSi) is an attractive choice when considering the utilization of
mesoporous materials in biomedical applications. The size of the pores, morphology and the …

High drug loading is one of the important issues in the drug delivery research, especially the
drug delivery system by oral administration. If high drug loading carriers are utilized the …