With almost 20 million new cases per year, cancer constitutes one of the most important
challenges for public health systems. Unlike traditional chemotherapy, targeted anti-cancer …

Introduction Luminescence-based technologies, specifically bioluminescence and
chemiluminescence, are powerful tools with extensive use in drug discovery. Production of …

Peptide secondary metabolites are common in nature and have diverse pharmacologically-
relevant functions, from antibiotics to cross-kingdom signaling. Here, we present a method to …

The characterization of protein-protein interactions (PPIs) is fundamental to the
understanding of biochemical processes. Many methods have been established to identify …

Purpose This review aims to provide a precise perceptive of the insulin-degrading enzyme
(IDE) and its relationship to type 2 diabetes (T2D), Alzheimer's disease (AD), obesity, and …

Transcription factors (TFs) form homo-or hetero-dimeric DNA binding complexes along with
associated co-regulators that can have transcriptional repressor or activator functions …

Pachyman, known as Poria cocos polysaccharides, refers to the bioactive compounds
isolated from Poria cocos. Pachyman is thought to exert cytoprotective action. However, the …

This study delves into the role of FBLN5 in pelvic organ prolapse (POP) and its molecular
mechanisms, focusing on the FOSL1/miR-222/MEIS1/COL3A1 axis. Gene relationships …

Proteomics is the large scale study of protein structure and function from biological systems
through protein identification and quantification.“Shotgun proteomics” or “bottom-up …

Avian coccidiosis is a common disease caused by Eimeria spp. In the genus Eimeria, the
species Eimeria tenella is an obligate intracellular parasite that invades mostly chicken …