Velocity-weighting & velocity-penalty MPC of an artificial pancreas: Improved safety & performance

R Gondhalekar, E Dassau, FJ Doyle III - Automatica, 2018 - Elsevier
Abstract A novel Model Predictive Control (MPC) law for the closed-loop operation of an
Artificial Pancreas (AP) to treat type 1 diabetes is proposed. The contribution of this paper is …

Invalidation and low-order model set for artificial pancreas robust control design

FD Bianchi, M Moscoso-Vásquez, P Colmegna… - Journal of Process …, 2019 - Elsevier
The purpose of this work is to compute a linear parameter-varying (LPV) model set that
describes the insulin-glucose dynamics in type 1 diabetes (T1D). This set includes a …

Treatment for T1DM patients by a neuro-fuzzy inverse optimal controller including multi-step prediction

YY Rios, JA García-Rodríguez, EN Sanchez, AY Alanis… - ISA transactions, 2022 - Elsevier
Diabetes Mellitus is a serious metabolic condition for global health associations. Recently,
the number of adults, adolescents and children who have developed Type 1 Diabetes …

Sample-data output-feedback parameter variable control of glucose for type 1 diabetes mellitus patients

K Hooshmandi, F Bayat - … of the Institute of Measurement and …, 2023 - journals.sagepub.com
This paper presents a new approach for nonlinear sampled-data output-feedback control of
blood glucose concentration (BGC) in patients with type 1 diabetes mellitus (T1DM). The …

Artificial pancreas: first clinical trials in Argentina

R Sánchez-Peña, P Colmegna, L Grosembacher… - IFAC-PapersOnLine, 2017 - Elsevier
The first clinical trials using an Artificial Pancreas (AP) in Latin America have been defined in
2 stages. The first stage was carried out in November 2016 with the UVA controller …

Synthesizing Robust Observer-Based Guaranteed Cost Linear Parameter Variable Control for Artificial Pancreas Systems Under Input Saturation

K Hooshmandi, S Mobayen, AA Zhilenkov - IEEE Access, 2024 - ieeexplore.ieee.org
The artificial pancreas (AP), commonly known as a closed-loop insulin delivery control
system, consists of three primary components: a glucose sensor for measuring blood …

Parameter estimation of a meal glucose–insulin model for TIDM patients from therapy historical data

OD Sánchez, E Ruiz‐Velázquez, AY Alanís… - IET systems …, 2019 - Wiley Online Library
The effect of meal on blood glucose concentration is a key issue in diabetes mellitus
because its estimation could be very useful in therapy decisions. In the case of type 1 …

Modelado y Simulación de Tecnologías para el Tratamiento de la Diabetes

N Rosales - 2020 - sedici.unlp.edu.ar
En las últimas dos décadas hubo un gran crecimiento en la investigación y el desarrollo de
sistemas de Páncreas Artificial (PA). Estos sistemas, compuestos por un lazo de control …

Plasma Glucose Reconstruction Based on Data Driven Real-Time Monitoring of CGM Devices

H Tang, Y Zhang, C Yang, L Zhou… - … on Medical Artificial …, 2024 - ieeexplore.ieee.org
Real time and accurate monitoring of plasma glucose concentration in diabetes patients is
necessary for their condition management. Continuous glucose monitoring (CGM) devices …

Hypoglycemia Prevention Using an Embedded Model Control with a Safety Scheme: In-silico Test

F Leon-Vargas, AL Jutinico… - Practical Applications of …, 2021 - Springer
Artificial pancreas systems have been designed and implemented over type 1 diabetes
patients to overcome glucose regulation problems of conventional therapies. However …