Optical coherence tomography for the evaluation of retinal and optic nerve morphology in animal subjects: practical considerations

GJ McLellan, CA Rasmussen - Veterinary ophthalmology, 2012 - Wiley Online Library
Optical coherence tomography (OCT) is a noninvasive, noncontact imaging technique
capable of producing high‐resolution images of the retina and optic nerve. These images …

relevant conditions and pathology of laboratory mice, rats, gerbils, Guinea pigs, hamsters, naked mole rats, and rabbits

TK Cooper, DK Meyerholz, AP Beck, MA Delaney… - ILAR …, 2021 - academic.oup.com
Animals are valuable resources in biomedical research in investigations of biological
processes, disease pathogenesis, therapeutic interventions, safety, toxicity, and …

Protective effect of intravitreal administration of exosomes derived from mesenchymal stem cells on retinal ischemia

E Moisseiev, JD Anderson, S Oltjen… - Current eye …, 2017 - Taylor & Francis
Purpose: Exosomes derived from human mesenchymal stem cells (hMSCs) cultured under
hypoxic conditions contain proteins and growth factors that promote angiogenesis. This …

Controlled release strategy designed for intravitreal protein delivery to the retina

V Delplace, A Ortin-Martinez, ELS Tsai, AN Amin… - Journal of Controlled …, 2019 - Elsevier
Therapeutic protein delivery directly to the eye is a promising strategy to treat retinal
degeneration; yet, the high risks of local drug overdose and cataracts associated with bolus …

In vivo wide-field multispectral scanning laser ophthalmoscopy–optical coherence tomography mouse retinal imager: longitudinal imaging of ganglion cells, microglia …

P Zhang, A Zam, Y Jian, X Wang, Y Li… - … of biomedical optics, 2015 - spiedigitallibrary.org
Scanning laser ophthalmoscopy (SLO) and optical coherence tomography (OCT) provide
complementary views of the retina, with the former collecting fluorescence data with good …

Quantitative fundus autofluorescence in mice: correlation with HPLC quantitation of RPE lipofuscin and measurement of retina outer nuclear layer thickness

JR Sparrow, A Blonska, E Flynn… - … & visual science, 2013 - iovs.arvojournals.org
Purpose.: Our study was conducted to establish procedures and protocols for quantitative
autofluorescence (qAF) measurements in mice, and to report changes in qAF, A2E …

Noninvasive imaging of the tree shrew eye: wavefront analysis and retinal imaging with correlative histology

BS Sajdak, AE Salmon, JA Cava, KP Allen… - Experimental eye …, 2019 - Elsevier
Tree shrews are small mammals with excellent vision and are closely related to primates.
They have been used extensively as a model for studying refractive development, myopia …

Diurnal rodents as pertinent animal models of human retinal physiology and pathology

DM Verra, BS Sajdak, DK Merriman, D Hicks - Progress in Retinal and Eye …, 2020 - Elsevier
This presentation will survey the retinal architecture, advantages, and limitations of several
lesser-known rodent species that provide a useful diurnal complement to rats and mice …

The temporal dynamic of bradykinin type 2 receptor effects reveals its neuroprotective role in the chronic phase of cerebral and retinal ischemic injury

H Justić, A Barić, M Ratko, I Šimunić… - Journal of Cerebral …, 2024 - journals.sagepub.com
The activation of the bradykinin type 2 receptor is intricately involved in acute post-ischemic
inflammatory responses. However, its precise role in different stages of ischemic injury …

Effects of intravitreal injection of human CD34+ bone marrow stem cells in a murine model of diabetic retinopathy

A Yazdanyar, P Zhang, C Dolf, Z Smit-McBride… - Experimental eye …, 2020 - Elsevier
Human CD34+ stem cells are mobilized from bone marrow to sites of tissue ischemia and
play an important role in tissue revascularization. This study used a murine model to test the …