Autoantibodies to synaptic receptors and neuronal cell surface proteins in autoimmune diseases of the central nervous system

J Dalmau, C Geis, F Graus - Physiological reviews, 2017 - journals.physiology.org
Investigations in the last 10 years have revealed a new category of neurological diseases
mediated by antibodies against cell surface and synaptic proteins. There are currently 16 …

Thymoma associated with autoimmune diseases: 85 cases and literature review

C Bernard, H Frih, F Pasquet, S Kerever… - Autoimmunity …, 2016 - Elsevier
Objectives To describe the clinical features, treatment, and outcome of autoimmune
diseases (AD) in a cohort of patients with thymoma. Design Pathological records from three …

Investigations in GABAA receptor antibody-associated encephalitis

M Spatola, M Petit-Pedrol, MM Simabukuro… - Neurology, 2017 - AAN Enterprises
Objective: To report the clinical features, comorbidities, receptor subunit targets, and
outcome in patients with anti-GABAA receptor (GABAAR) encephalitis. Methods: Clinical …

Immune therapy in autoimmune encephalitis: a systematic review

M Nosadini, SS Mohammad… - Expert review of …, 2015 - Taylor & Francis
We have reviewed the literature of immune therapy in autoimmune encephalitis associated
with antibodies to cell surface antigens including N-methyl-D-aspartate receptor (NMDAR) …

Anti‐LGI1 encephalitis is strongly associated with HLA‐DR7 and HLA‐DRB4

A van Sonderen, DL Roelen, JA Stoop… - Annals of …, 2017 - Wiley Online Library
Leucine‐rich glioma‐inactivated1 (LGI1) encephalitis is an antibody‐associated
inflammation of the limbic area. An autoimmune etiology is suspected but not yet proven. We …

Origins and immunopathogenesis of autoimmune central nervous system disorders

S Ramanathan, F Brilot, SR Irani, RC Dale - Nature Reviews Neurology, 2023 - nature.com
The field of autoimmune neurology is rapidly evolving, and recent discoveries have
advanced our understanding of disease aetiologies. In this article, we review the key …

Updates in the diagnosis and treatment of paraneoplastic neurologic syndromes

RS Grativvol, WCP Cavalcante, LHM Castro… - Current oncology …, 2018 - Springer
The disorders of the central nervous system associated with cancer by remote immune-
mediated mechanisms are a heterogeneous group. These disorders encompass the classic …

MRI characteristics of autoimmune encephalitis with autoantibodies to GABAA receptor: a case series

B Deng, M Cai, Y Qiu, X Liu, H Yu, X Zhang… - Neurology …, 2022 - AAN Enterprises
Background and Objectives To characterize the clinical and neuroimaging phenotypes of
patients with autoantibodies to γ-aminobutyric acid type A receptor (GABAAR). Methods Ten …

GABAA receptor autoimmunity: A multicenter experience

K O'Connor, P Waters, L Komorowski… - Neurology …, 2019 - AAN Enterprises
Objective We sought to validate methods for detection and confirmation of GABAA receptor
(R)-IgG and clinically characterize seropositive cases. Methods Archived serum and CSF …

Frequency of synaptic autoantibody accompaniments and neurological manifestations of thymoma

A Zekeridou, A McKeon, VA Lennon - JAMA neurology, 2016 - jamanetwork.com
Importance Thymoma is commonly recognized in association with paraneoplastic
autoimmune myasthenia gravis (MG), an IgG–mediated impairment of synaptic transmission …