COVID-19, immune system response, hyperinflammation and repurposingantirheumatic drugs

A Tufan, AA Güler… - Turkish journal of medical …, 2020 - journals.tubitak.gov.tr
Abstract In the Wuhan Province of China, in December 2019, the novel coronavirus 2019
(COVID-19) has caused a severe involvement of the lower respiratory tract leading to an …

COVID-19, mast cells, cytokine storm, psychological stress, and neuroinflammation

D Kempuraj, GP Selvakumar, ME Ahmed… - The …, 2020 - journals.sagepub.com
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is a new pandemic infectious disease that originated in China …

Elevated troponin in patients with coronavirus disease 2019: possible mechanisms

G Tersalvi, M Vicenzi, D Calabretta, L Biasco… - Journal of cardiac …, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a pandemic that has affected more than
1.8 million people worldwide, overwhelmed health care systems owing to the high …

[HTML][HTML] NF-κB pathway as a potential target for treatment of critical stage COVID-19 patients

R Kircheis, E Haasbach, D Lueftenegger… - Frontiers in …, 2020 - frontiersin.org
Patients infected with SARS-CoV-2 show a wide spectrum of clinical manifestations ranging
from mild febrile illness and cough up to acute respiratory distress syndrome, multiple organ …

[HTML][HTML] SARS-CoV-2 induces transcriptional signatures in human lung epithelial cells that promote lung fibrosis

J Xu, X Xu, L Jiang, K Dua, PM Hansbro, G Liu - Respiratory research, 2020 - Springer
Background Severe acute respiratory syndrome (SARS)-CoV-2-induced coronavirus
disease-2019 (COVID-19) is a pandemic disease that affects> 2.8 million people worldwide …

[HTML][HTML] Can Zn be a critical element in COVID-19 treatment?

MT Rahman, SZ Idid - Biological trace element research, 2021 - Springer
The current COVID-19 pandemic caused by SARS-CoV-2 has prompted investigators
worldwide to search for an effective anti-viral treatment. A number of anti-viral drugs such as …

[PDF][PDF] IL-6 and IL-10 as predictors of disease severity in COVID-19 patients: results from meta-analysis and regression

SK Dhar, K Vishnupriyan, S Damodar, S Gujar, M Das - Heliyon, 2021 - cell.com
Abstract Aims SARS-CoV-2, an infectious agent behind the ongoing COVID-19 pandemic,
induces high levels of cytokines such as IL-1, IL-2, IL-4, IL-6, IL-10, TNF-α, IFN-γ etc in …

The possible mechanisms of action of 4-aminoquinolines (chloroquine/hydroxychloroquine) against Sars-Cov-2 infection (COVID-19): A role for iron homeostasis?

EQ Roldan, G Biasiotto, P Magro, I Zanella - Pharmacological research, 2020 - Elsevier
The anti-malarial drugs chloroquine (CQ) and primarily the less toxic hydroxychloroquine
(HCQ) are currently used to treat autoimmune diseases for their immunomodulatory and anti …

[HTML][HTML] Coronavirus disease pandemic (COVID-19): challenges and a global perspective

YS Malik, N Kumar, S Sircar, R Kaushik, S Bhat… - Pathogens, 2020 - mdpi.com
The technology-driven world of the 21st century is currently confronted with a major threat to
humankind, represented by the coronavirus disease (COVID-19) pandemic, caused by the …

Sex hormones and novel corona virus infectious disease (COVID-19)

RA Al-Lami, RJ Urban, E Volpi, AMA Algburi… - Mayo Clinic …, 2020 - Elsevier
Given the rapid spread of the coronavirus disease 2019 (COVID-19) pandemic and its
overwhelming effect on health care systems and the global economy, innovative therapeutic …