Role of Post-Transcriptional Regulation in Learning and Memory in Mammals

CM Di Liegro, G Schiera, G Schirò, I Di Liegro - Genes, 2024 - mdpi.com
After many decades, during which most molecular studies on the regulation of gene
expression focused on transcriptional events, it was realized that post-transcriptional control …

[HTML][HTML] Dysregulated expression of cholesterol biosynthetic genes in Alzheimer's disease alters epigenomic signatures of hippocampal neurons

I Paiva, J Seguin, I Grgurina, AK Singh, B Cosquer… - Neurobiology of …, 2024 - Elsevier
Aging is the main risk factor of cognitive neurodegenerative diseases such as Alzheimer's
disease, with epigenome alterations as a contributing factor. Here, we compared …

From use of omics to systems biology: Identifying therapeutic targets for amyotrophic lateral sclerosis.

L Castelli, R Vasta, SP Allen, R Waller… - International Review …, 2024 - europepmc.org
Amyotrophic lateral sclerosis (ALS) is a heterogeneous progressive neurodegenerative
disorder with available treatments such as riluzole and edaravone extending survival by an …