Obesity and its complications have become a prominent global public health problem that
severely threatens human health. Melatonin, originally known as an effective antioxidant, is …

Angiogenesis depends on proangiogenic and anti-angiogenic molecules that regulate
endothelial cell proliferation and migration. Well-regulated angiogenesis plays a pivotal role …

The endothelium, which forms the inner cellular lining of blood vessels and lymphatics, is a
highly metabolically active organ that is involved in many physiopathological processes …

The pineal gland is a neuroendocrine gland which produces melatonin, a neuroendocrine
hormone with critical physiological roles in the circadian rhythm and sleep-wake cycle …

The production of the pineal hormone melatonin is synchronized with day-night cycle via
multisynaptic pathway including suprachiasmatic nucleus linking several physiological …

In the last decade, melatonin has been found to be highly protective against damage to
macromolecules resulting from oxygen and nitrogen-based reactants. Considering this …

Atherosclerosis is a chronic vascular disease in which oxidative stress and inflammation are
commonly implicated as major causative factors. Identification of novel strategies that …

In recent days, the hike in obesity‐mediated epidemics across the globe and the prevalence
of obesity‐induced cardiovascular disease has become one of the chief grounds for …

Melatonin, which is synthesized in the pineal gland and other tissues, has a variety of
physiological, immunological, and biochemical functions. It is a direct scavenger of free …

Background Epidemiological evidence suggests that melatonin has some effects on the
serum lipid. However, these results are controversial. The aim of this systematic review and …