Influence of cell shape, inhomogeneities and diffusion barriers in cell polarization models

W Giese, M Eigel, S Westerheide, C Engwer… - Physical …, 2015 - iopscience.iop.org
In silico experiments bear the potential for further understanding of biological transport
processes by allowing a systematic modification of any spatial property and providing …

Gradient sensing by a bistable regulatory motif enhances signal amplification but decreases accuracy in individual cells

R Sharma, E Roberts - Physical Biology, 2016 - iopscience.iop.org
Many vital eukaryotic cellular functions require the cell to respond to a directional gradient of
a signaling molecule. The first two steps in any eukaryotic chemotactic/chemotropic pathway …