The many applications of engineered bacteriophages—An overview

B Gibb, P Hyman, CL Schneider - Pharmaceuticals, 2021 - mdpi.com
Since their independent discovery by Frederick Twort in 1915 and Felix d'Herelle in 1917,
bacteriophages have captured the attention of scientists for more than a century. They are …

Bacteriophage-based biosensors: A platform for detection of foodborne bacterial pathogens from food and environment

RR Al-Hindi, AD Teklemariam, MG Alharbi, I Alotibi… - Biosensors, 2022 - mdpi.com
Foodborne microorganisms are an important cause of human illness worldwide. Two-thirds
of human foodborne diseases are caused by bacterial pathogens throughout the globe …

Engineered reporter phages for detection of Escherichia coli, Enterococcus, and Klebsiella in urine

S Meile, J Du, S Staubli, S Grossmann… - Nature …, 2023 - nature.com
The rapid detection and species-level differentiation of bacterial pathogens facilitates
antibiotic stewardship and improves disease management. Here, we develop a rapid …

Reporter phage-based detection of bacterial pathogens: design guidelines and recent developments

S Meile, S Kilcher, MJ Loessner, M Dunne - Viruses, 2020 - mdpi.com
Fast and reliable detection of bacterial pathogens in clinical samples, contaminated food
products, and water supplies can drastically improve clinical outcomes and reduce the socio …

Recent progress in the detection of bacteria using bacteriophages: A review

J Paczesny, Ł Richter, R Hołyst - Viruses, 2020 - mdpi.com
Bacteria will likely become our most significant enemies of the 21st century, as we are
approaching a post-antibiotic era. Bacteriophages, viruses that infect bacteria, allow us to …

Application of bacteriophages in nanotechnology

J Paczesny, K Bielec - Nanomaterials, 2020 - mdpi.com
Bacteriophages (phages for short) are viruses, which have bacteria as hosts. The single
phage body virion, is a colloidal particle, often possessing a dipole moment. As such …

Optimization of T4 phage engineering via CRISPR/Cas9

MM Duong, CM Carmody, Q Ma, JE Peters… - Scientific reports, 2020 - nature.com
A major limitation hindering the widespread use of synthetic phages in medical and
industrial settings is the lack of an efficient phage-engineering platform. Classical T4 phage …

Emerging investigator series: bacteriophages as nano engineering tools for quality monitoring and pathogen detection in water and wastewater

F Bayat, TF Didar, Z Hosseinidoust - Environmental Science: Nano, 2021 - pubs.rsc.org
Waterborne bacterial pathogens are a major public health concern worldwide, taking many
lives and imposing huge economical burden. Rapid and specific detection of pathogens and …

A systematic review from basics to omics on bacteriophage applications in poultry production and processing

MR Islam, CE Martinez-Soto, JT Lin… - Critical Reviews in …, 2023 - Taylor & Francis
The growing human population is currently facing an unprecedented challenge on global
food production and sustainability. Despite recognizing poultry as one of the most successful …

Rapid, sensitive, and low-cost detection of Escherichia coli bacteria in contaminated water samples using a phage-based assay

LF Alonzo, P Jain, T Hinkley, N Clute-Reinig… - Scientific Reports, 2022 - nature.com
Inadequate drinking water quality is among the major causes of preventable mortality,
predominantly in young children. Identifying contaminated water sources remains a …