The translaminar pressure gradient (TLPG) refers to two forces at the lamina cribosa of the
optic nerve: the anteriorly acting intracranial pressure (ICP), and posteriorly-acting …

Nocturnal intraocular pressure (IOP) profiling has shown that the peak IOP usually occurs at
night, particularly in patients with glaucoma. Multiple studies have demonstrated that these …

Background As a key element of ocular accommodation, the inherent mechanical stiffness
gradient and the gradient refractive index (GRIN) of the crystalline lens determine its …

We read with interest Quinn et al.'s paper on the association of topical glaucoma
medications with lacrimal drainage obstruction and eyelid malposition [1]. The authors …

Objective: To evaluate the safety and effectiveness of the Multi-Pressure Dial (MPD) system,
a device that applies periocular negative pressure to lower intraocular pressure (IOP) …

Introduction To investigate the effect of applying negative pressure (vacuum) to the
periocular space on intraocular pressure (IOP) and retrobulbar pressure (RBP) by use of the …

Objective: To determine whether the intraocular pressure (IOP)-lowering effects of the BGS
are accompanied by changes in retinal thickness measured by OCT, retinal vascular density …

Purpose To evaluate the effects of pressure changes induced by a multipressure dial (MPD)
on circumpapillary retinal nerve fiber layer (RNFL) and capillary density (CD) measurements …

Introduction The purpose of this study was to investigate the short-term safety and feasibility
of negative pressure application by the Multi-Pressure Dial (MPD) System to lower nocturnal …

Purpose: The purpose of this study was to evaluate the effects of negative periocular
pressure (NPP), and concomitant intraocular pressure (IOP) lowering, on the biomechanics …