Revisiting the role of neurotransmitters in epilepsy: An updated review

E Akyuz, AK Polat, E Eroglu, I Kullu, E Angelopoulou… - Life sciences, 2021 - Elsevier
Epilepsy is a neurologicaldisorder characterized by persistent predisposition to recurrent
seizurescaused by abnormal neuronal activity in the brain. Epileptic seizures maydevelop …

Intranasally administered pitavastatin ameliorates pentylenetetrazol-induced neuroinflammation, oxidative stress and cognitive dysfunction

A Iqubal, S Sharma, K Sharma, A Bhavsar, I Hussain… - Life sciences, 2018 - Elsevier
Aim The present study aimed to evaluate the neuroprotective potential of intranasally
administered pitavastatin in the PTZ-induced kindling model. Materials and methods …

Caffeine attenuates seizure and brain mitochondrial disruption induced by Tramadol: the role of adenosinergic pathway

M Samadi, F Shaki, B Bameri, M Fallah… - Drug and chemical …, 2021 - Taylor & Francis
Tramadol (TR) is an analgesic drug used to treat moderate-to-severe pain but it induces
seizure even at therapeutic doses. The exact mechanism of TR-inducing seizure is not clear …

Antagonism of adenosinergic system decrease SWD occurrence via an increment in thalamic NFkB and IL-6 in absence epilepsy

F Dede, S Karadenizli, OD Ozsoy, FC Eraldemir… - Journal of …, 2019 - Elsevier
Epilepsy is a major pathological condition, characterized by recurrent seizures and affecting
approximately 1% of the population. Many studies have shown a relationship between …

Effects of leptin, ghrelin and neuropeptide y on spike-wave discharge activity and certain biochemical parameters in WAG/Rij rats with genetic absence epilepsy

B Oztas, D Sahin, H Kir, S Kuskay, N Ates - Journal of Neuroimmunology, 2021 - Elsevier
This study aimed to evaluate the effects of leptin, ghrelin and neuropeptide-Y on the
development of nonconvulsive seizure activity and their role on combating oxidative stress …

The effects of acute and chronic infusions of dexamethasone on audiogenic seizures and catalepsy in rats of Krushinsky–Molodkina and “0” Strains

NM Surina, IB Fedotova, II Poletaeva - Journal of Evolutionary …, 2022 - Springer
Dexamethasone is a synthetic glucocorticosteroid with anti–inflammatory and
immunosuppressive effects. In order to identify new targets for pharmacotherapy, as well as …

[PDF][PDF] The comparison of inflammatory markers in pentylenetetrazole-induced acute epileptic seizure model and chronic epilepsy model in rats

AŞ Taşkıran, Y Taştemur - Cumhuriyet Science Journal, 2020 - dergipark.org.tr
Recent studies have provided important evidence that neuroinflammation has an effective
role in epilepsy pathophysiology. However, it is not clear that the occurrence of …

Decreased ERp57 expression in WAG/Rij rats thalamus and cortex: possible correlation with absence epilepsy

D Sahin, S Karadenizli, M Kasap… - Protein and Peptide …, 2018 - ingentaconnect.com
Background: The role of intracellular proteins in the pathogenesis of absence epilepsy were
mentioned. These proteins are thought to be related to energy generation, signal …

Ursolic acid along with caprylic acid ameliorates pentylenetetrazole induced seizures like behavior in adult zebrafish

D Sharma, S Kaur, L Kapil, C Singh, A Singh - 2022 - researchsquare.com
Background: Epilepsy is a neurological disorder characterized by recurrent unprovoked
seizures. Despite the existence of more than 20 anti-epileptic drugs there is still a need for …

[PDF][PDF] ВЛИЯНИЕ ОСТРОГО И ХРОНИЧЕСКОГО ВВЕДЕНИЯ ДЕКСАМЕТАЗОНА НА АУДИОГЕННЫЕ СУДОРОГИ И КАТАЛЕПСИЮ КРЫС ЛИНИЙ …

НМ Сурина, ИБ Федотова… - … журнал им. ИМ …, 2022 - rusjphysiol.org
Аннотация Дексаметазон–синтетический глюкокортикостероид, обладающий
противовоспалительным и иммуносупрессивным действием. С целью выявления новых …