Loss of photoreceptors due to retinal degeneration is a major cause of blindness in the
developed world. While no effective treatment is currently available, cell replacement …

Normal tables of development are essential for studies of embryogenesis, serving as an
important resource for model organisms, including the frog Xenopus laevis. Xenopus has …

Tumorigenic cells are similar to neural stem cells or embryonic neural cells in regulatory
networks, tumorigenicity and pluripotent differentiation potential. By integrating the evidence …

Abstract Xenbase (http://www. xenbase. org), the Xenopus frog model organism database,
integrates a wide variety of data from this biomedical model genus. Two closely related …

Xenbase, the Xenopus model organism database (www. xenbase. org), is a cloud‐based,
web‐accessible resource that integrates the diverse genomic and biological data from …

Investigating neural stem cell (NSC) behaviour in vivo, which is a major area of research,
requires NSC models to be developed. We carried out a multilevel characterisation of the …

The retina of fish and amphibian contains genuine neural stem cells located at the most
peripheral edge of the ciliary marginal zone (CMZ). However, their cell-of-origin as well as …

In lower vertebrates, retinal stem cells (RSCs) capable of producing all retinal cell types are
a resource for retinal tissue growth throughout life. However, the embryonic origin of RSCs …

Wnt proteins form a family of highly conserved secreted molecules that are critical mediators
of cell-cell signaling during embryogenesis. Partial data on Wnt activity in different tissues …

Xenbase is the Xenopus model organism database (www. xenbase. org), a web-accessible
resource that integrates the diverse genomic and biological data for Xenopus research. It …