Prospects for in vivo Raman spectroscopy

EB Hanlon, R Manoharan, TW Koo… - Physics in Medicine …, 2000 - iopscience.iop.org
Raman spectroscopy is a potentially important clinical tool for real-time diagnosis of disease
and in situevaluation of living tissue. The purpose of this article is to review the biological …

Fiber optic probes for biomedical optical spectroscopy

U Utzinger, RR Richards-Kortum - Journal of biomedical …, 2003 - spiedigitallibrary.org
Fiber optic probes are a key element for biomedical spectroscopic sensing. We review the
use of fiber optic probes for optical spectroscopy, focusing on applications in turbid media …

Raman spectroscopy: guiding light for the extracellular matrix

MS Bergholt, A Serio, MB Albro - Frontiers in bioengineering and …, 2019 - frontiersin.org
The extracellular matrix (ECM) consists of a complex mesh of proteins, glycoproteins, and
glycosaminoglycans, and is essential for maintaining the integrity and function of biological …

Near‐infrared Raman spectroscopy for in vitro detection of cervical precancers

A Mahadevan‐Jansen, MF Mitchell… - Photochemistry and …, 1998 - Wiley Online Library
In this study, we investigate the potential of near‐infrared Raman spectroscopy to
differentiate cervical precancers from normal tissues, inflammation and metaplasia and to …

Raman microspectroscopic model of human breast tissue: implications for breast cancer diagnosis in vivo

KE Shafer‐Peltier, AS Haka… - Journal of Raman …, 2002 - Wiley Online Library
Raman spectroscopy has the potential to provide real‐time, in situ diagnosis of breast
cancer during needle biopsy or surgery via an optical fiber probe. Understanding the …

Study of fiber-optic probes for in vivo medical Raman spectroscopy

MG Shim, BC Wilson, E Marple, M Wach - Applied Spectroscopy, 1999 - opg.optica.org
Recent reports indicate that useful diagnostic information can be obtained from ex vivo
tissue by using near-infrared Raman spectroscopy. A fiber-optic-based Raman system has …

[HTML][HTML] Raman spectroscopy detects biochemical changes due to proliferation in mammalian cell cultures

KW Short, S Carpenter, JP Freyer, JR Mourant - Biophysical journal, 2005 - cell.com
Raman spectra of cells and nuclei from cultures in the plateau (nonproliferating) and
exponential (proliferating) phases of growth were measured and show that Raman …

Histochemical analysis of biological tissues using Raman spectroscopy

R Manoharan, Y Wang, MS Feld - … Acta Part A: Molecular and Biomolecular …, 1996 - Elsevier
This paper reviews the application of the Raman spectroscopic technique for analysis of
biological tissue. The advantages and disadvantages of visible, near-IR and UV excitations …

Raman spectra of biological samples: A study of preprocessing methods

NK Afseth, VH Segtnan, JP Wold - Applied spectroscopy, 2006 - opg.optica.org
In this study preprocessing of Raman spectra of different biological samples has been
studied, and their effect on the ability to extract robust and quantitative information has been …

Quantifying adhesive penetration in adhesive/dentin interface using confocal Raman microspectroscopy

Y Wang, P Spencer - … Materials Research: An Official Journal of …, 2002 - Wiley Online Library
Confocal Raman microspectroscopy (CRM) provides an important and novel means of
analyzing the chemical composition of the adhesive/dentin (a/d) interface. The purpose of …