So far, the search for a cure for Alzheimer Disease (AD) has been unsuccessful. The only
approved drugs attenuate some symptoms, but do not halt the progress of this disease …

The origins of Alzheimer's disease (AD) and Parkinson's disease (PD) involve genetic
mutations, epigenetic changes, neurotoxin exposure and gut microbiota dysregulation. The …

Alzheimer's disease (AD) is a leading cause of cognitive decline in the aging population,
presenting a critical need for early diagnosis and effective prognostic tools. Epigenetic …

While identification of epigenetic changes in individuals with psychiatric dysfunctions such
as post-traumatic stress disorder (PTSD) is paramount to genomic research, there is no …

Different cell types in the brain play distinct roles in Alzheimer's disease (AD) progression.
Late onset AD (LOAD) is a complex disease, with a large genetic component, but many risk …

Background Striatal dopamine transporter (DAT) binding is a sensitive and specific
endophenotype for detecting dopaminergic deficits across Parkinson's disease (PD) …

Recently, there has been a growing interest in variable selection for causal inference within
the context of high-dimensional data. However, when the outcome exhibits a skewed …

Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a rare inherited
condition described worldwide and characterized by a wide spectrum of heterogeneity in …

This study aimed to investigate the cross-sectional associations between regional
Alzheimer's disease (AD) biomarkers, including tau, β-amyloid (Aβ), and brain volume …

Mediation analysis plays a crucial role in causal inference as it can investigate the pathways
through which treatment influences outcome. Most existing mediation analysis assumes that …