Tuberculosis (TB) remains a global health problem despite almost universal efforts to
provide patients with highly effective chemotherapy, in part, because many infected …

Aminoglycosides are one of the common classes of antibiotics that have been widely used
for treating infections caused by pathogenic bacteria. The mechanism of bactericidal action …

Screening strategies for antituberculosis compounds using Mycobacterium tuberculosis are
time consuming and require biosafety level 3 (BSL3) facilities, which makes the …

Arabinogalactan (AG) participates in forming the cell wall core of mycobacteria, a structure
known as the mAGP complex. Few studies have reported the virulence of inartificial AG or its …

Mycobacterium marinum is a model organism for pathogenic Mycobacterium species,
including Mycobacterium tuberculosis, the causative agent of tuberculosis. These pathogens …

Shigella flexneri is a facultative intracellular pathogen that causes shigellosis, a human
diarrheal disease characterized by the destruction of the colonic epithelium. Novel …

The ESX-5 secretion system is essential for the viability and virulence of slow-growing
pathogenic mycobacterial species. In this study, we identified a 1, 2, 4-oxadiazole derivative …

Tuberculosis (TB) is caused by infection with Mycobacterium tuberculosis (Mtb), which has a
unique resistance to many antimicrobial agents. TB has emerged as a significant worldwide …

Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), is a major health threat listed
among the top 10 causes of death worldwide. Treatment of multidrug-resistant Mtb requires …

Intracellular pathogens interact with host systems in intimate ways to sustain a pathogenic
lifestyle. Consequently, these interactions can potentially be targets of host‐directed …