Cardiometabolic complications in youth with perinatally acquired HIV in the era of antiretroviral therapy

S Dirajlal-Fargo, GA McComsey - Current HIV/AIDS Reports, 2021 - Springer
Abstract Purpose of Review Antiretroviral therapy (ART) scale-up has dramatically reduced
rates of pediatric HIV mortality and morbidity. Children living with perinatally acquired HIV …

Noncommunicable diseases in adolescents with perinatally acquired HIV-1 infection in high-income and low-income settings

S Innes, K Patel - Current Opinion in HIV and AIDS, 2018 - journals.lww.com
As perinatally HIV-infected children age into adolescence and adulthood with effective long-
term ART, it is necessary to continue to evaluate their risks for noninfectious comorbidities …

Longitudinal comparison of insulin resistance and dyslipidemia in children with and without perinatal HIV infection in South Africa

C Davies, F Vaida, K Otwombe, MF Cotton, S Browne… - AIDS, 2023 - journals.lww.com
Methods: Four hundred and eighty-five children (141 CHIV, 169 CHEU, 175 CHU) aged 5–
16 years, previously part of CHER and P1060 trials, were followed annually at Tygerberg …

Growing up with perinatal HIV

PM Flynn, EJ Abrams - Aids, 2019 - journals.lww.com
Abstract The World Health Organization estimates that over four million children have been
infected with HIV, most via perinatal transmission. The availability of safe and effective …

Factors associated with insulin resistance in a longitudinal study of Ugandan youth with and without HIV

S Dirajlal-Fargo, M Strah, K Ailstock, A Sattar… - AIDS, 2024 - journals.lww.com
Prospective investigations from sub-Saharan Africa on metabolic complications in youth with
perinatally acquired HIV (PHIV) are lacking. We investigated the changes in insulin …

Changes in insulin sensitivity over time and associated factors in HIV-infected adolescents

ME Geffner, K Patel, DL Jacobson, J Wu, TL Miller… - Aids, 2018 - journals.lww.com
Objective: To compare prevalence of insulin resistance between perinatally HIV-infected
(PHIV+) and perinatally HIV-exposed, but uninfected adolescents (PHEU), determine …

Longitudinal changes in body fat and metabolic complications in young people with perinatally acquired HIV

S Dirajlal‐Fargo, DL Jacobson, W Yu, A Mirza… - HIV …, 2024 - Wiley Online Library
Background The role of body fat on metabolic complications remains poorly understood in
young people living with perinatally acquired HIV (YPHIV). Objective Our objective was to …

Insulin resistance and intestinal integrity in children with and without HIV infection in Uganda

S Dirajlal‐Fargo, L Shan, A Sattar, E Bowman… - HIV …, 2020 - Wiley Online Library
Objectives The risk of cardiometabolic complications in children with perinatally acquired
HIV infection (PHIVs) and in perinatally HIV‐exposed but uninfected children (HEUs) and its …

Cardiometabolic complications in children and adolescents with HIV on antiretroviral therapy

C Muccini, M Bottanelli, A Castagna… - Expert Opinion on Drug …, 2024 - Taylor & Francis
Introduction The course of HIV infection has changed radically with the introduction of
antiretroviral therapy (ART), which has significantly reduced mortality and improved quality …

Impaired fasting glucose levels among perinatally HIV-infected adolescents and youths in Dar es Salaam, Tanzania

L Nkinda, E Buberwa, P Memiah… - Frontiers in …, 2022 - frontiersin.org
Objective This study assessed impaired fasting glucose and associated factors among
perinatally HIV-infected adolescents and youths in Dar es salaam Tanzania. Background …