The cognitive symptoms of schizophrenia are largely resistant to current treatment and are
thus a life-long burden of the illness. Studies of cognitive symptoms have commonly focused …

Cannabis use is considered a contributory cause of schizophrenia and psychotic illness.
However, only a small proportion of cannabis users develop psychosis. This can partly be …

Fibromyalgia (FM) is a disorder of unknown aetiology, characterized by chronic widespread
pain, stiffness and sleep disturbances. In addition, patients frequently complain of memory …

The C957T polymorphism of the human dopamine D2 receptor gene (DRD2) regulates
DRD2 availability in striatum in vivo. Specifically, the T allele predicts high DRD2 availability …

Two limiting factors of dopamine activity are the catechol-o-methyltransferase (COMT) and
the dopamine transporter (DAT), which terminate dopamine activity by degradation and …

Several single nucleotide polymorphisms have been linked to neural and cognitive variation
in healthy adults. We examined contribution of three polymorphisms frequently associated …

Smoking cannabis daily doubles an individual's risk of developing a psychotic disorder, yet
indicators of specific vulnerability have proved largely elusive. Genetic variation is one …

Insufficient sleep is a global public health problem resulting in catastrophic accidents,
increased mortality, and hundreds of billions of dollars in lost productivity. Yet the effect of …

The co-occurrence of schizophrenia (SCZ) and type 2 diabetes mellitus (T2D) has been well
documented. This review article focuses on the hypothesis that the co-occurrence of SCZ …

The C957T (rs6277) single nucleotide polymorphism (SNP) of the human dopamine D2
receptor (DRD2) gene (DRD2) affects DRD2 mRNA stability and has been shown to predict …