Adipogenesis is the process by which precursor stem cells differentiate into lipid laden
adipocytes. Adipogenesis is regulated by a complex and highly orchestrated gene …

Obesity is now a widespread disorder, and its prevalence has become a critical concern
worldwide, due to its association with common co-morbidities like cancer, cardiovascular …

Bone marrow‐derived mesenchymal stem cells (MSCs) are multipotent progenitors that can
commit to osteoblast, chondrocyte, adipocyte, and several other lineages. The proper …

Physical loading is a potent stimulus required to maintain bone homeostasis, partly through
the renewal and osteogenic differentiation of mesenchymal stem cells (MSCs). However, the …

Adipose-derived stromal cells (ASCs) present a great potential for tissue engineering, as
they are capable of differentiating into osteogenic and adipogenic cell types, among others …

Obesity is a growing health problem commonly associated with numerous metabolic
disorders including type 2 diabetes, hypertension, cardiovascular disease, and some forms …

As motile organelles and sensors, cilia play pivotal roles in cell physiology, development
and organ homeostasis. Ciliary defects are associated with a class of cilia-related diseases …

Hedgehog (Hh) signalling has been implicated in the development of osteoblasts and
osteoclasts whose balanced activities are critical for proper bone formation. As many mouse …

The differentiation capabilities of mesenchymal stem cells (MSCs) compromise with age and
with in vitro passages which could impair the efficacy of cell therapy and tissue engineering …

Pluripotent stem cells are a promising tool for mechanistic studies of tissue development,
drug screening, and cell-based therapies. Here, we report an effective and mass-producing …