Current challenges in designer cellulosome engineering

B Lamote, MJM da Fonseca, J Vanderstraeten… - Applied Microbiology …, 2023 - Springer
Designer cellulosomes (DCs) are engineered multi-enzyme complexes, comprising
carbohydrate-active enzymes attached to a common backbone, the scaffoldin, via high …

Cryptic diversity of cellulose-degrading gut bacteria in industrialized humans

S Moraïs, S Winkler, A Zorea, L Levin, FSP Nagies… - Science, 2024 - science.org
Humans, like all mammals, depend on the gut microbiome for digestion of cellulose, the
main component of plant fiber. However, evidence for cellulose fermentation in the human …

[HTML][HTML] Cellulosomal hemicellulases: indispensable players for ensuring effective lignocellulose bioconversion

M Xiao, YJ Liu, EA Bayer, A Kosugi, Q Cui, Y Feng - Green Carbon, 2024 - Elsevier
The bioconversion of lignocellulose has attracted global attention, due to the significant
potential of agricultural and forestry wastes as renewable zero-carbon resources and the …

Phylogenomics and genetic analysis of solvent-producing Clostridium species

RO Jensen, F Schulz, S Roux, DM Klingeman… - Scientific data, 2024 - nature.com
The genus Clostridium is a large and diverse group within the Bacillota (formerly Firmicutes),
whose members can encode useful complex traits such as solvent production, gas …

Abundant taxa and favorable pathways in the microbiome of soda-saline lakes in Inner Mongolia

D Zhao, S Zhang, Q Xue, J Chen, J Zhou… - Frontiers in …, 2020 - frontiersin.org
Soda-saline lakes are a special type of alkaline lake in which the chloride concentration is
greater than the carbonate/bicarbonate concentration. Due to the high pH and a usually …

Multi-omic directed discovery of cellulosomes, polysaccharide utilization loci, and lignocellulases from an enriched rumen anaerobic consortium

G Tomazetto, AC Pimentel, D Wibberg… - Applied and …, 2020 - Am Soc Microbiol
Lignocellulose is one of the most abundant renewable carbon sources, representing an
alternative to petroleum for the production of fuel and chemicals. Nonetheless, the …

A cellulosomal double‐dockerin module from Clostridium thermocellum shows distinct structural and cohesin‐binding features

C Chen, H Yang, S Dong, C You, S Moraïs… - Protein …, 2024 - Wiley Online Library
Cellulosomes are intricate cellulose‐degrading multi‐enzymatic complexes produced by
anaerobic bacteria, which are valuable for bioenergy development and biotechnology …

Shift in rhizospheric and endophytic microbial communities of dominant plants around Sunit Alkaline Lake

J Luo, T Liu, F Diao, B Hao, ZC Zhang, Y Hou… - Science of The Total …, 2023 - Elsevier
Alkaline lakes are a special type of extreme saline-alkali ecosystem, and the dominant
plants store a large number of microbial resources with salinity-tolerant or growth-promoting …

Mapping the deformability of natural and designed cellulosomes in solution

J Dorival, S Moraïs, A Labourel, B Rozycki… - … for biofuels and …, 2022 - Springer
Background Natural cellulosome multi-enzyme complexes, their components, and
engineered 'designer cellulosomes'(DCs) promise an efficient means of breaking down …

Phylogenomics, CAZyome and core secondary metabolome of Streptomyces albus species

MS Vela Gurovic, ML Díaz, CA Gallo… - Molecular Genetics and …, 2021 - Springer
A phylogenomic study conducted with different bioinformatic tools such as TYGS, REALPHY
and AAI comparisons revealed a high rate of misidentified Streptomyces albus genomes in …