Progresses in predicting post-translational modification
KC Chou - International Journal of Peptide Research and …, 2020 - Springer
Identification of the sites of post-translational modifications (PTMs) in protein, RNA, and DNA
sequences is currently a very hot topic. This is because the information thus obtained is very …
sequences is currently a very hot topic. This is because the information thus obtained is very …
Insights into Machine Learning-based approaches for Virtual Screening in Drug Discovery: Existing strategies and streamlining through FP-CADD
Background: Machine learning is an active area of research in computer science by the
availability of big data collection of all sorts prompting interest in the development of novel …
availability of big data collection of all sorts prompting interest in the development of novel …
SPalmitoylC-PseAAC: A sequence-based model developed via Chou's 5-steps rule and general PseAAC for identifying S-palmitoylation sites in proteins
S-Palmitoylation is a uniquely reversible and biologically important post-translational
modification as it plays an essential role in a variety of cellular processes including signal …
modification as it plays an essential role in a variety of cellular processes including signal …
SPrenylC-PseAAC: A sequence-based model developed via Chou's 5-steps rule and general PseAAC for identifying S-prenylation sites in proteins
The protein prenylation (or S-prenylation) is one of the most essential modifications,
required for the association of membrane of a plethora of signalling proteins with the key …
required for the association of membrane of a plethora of signalling proteins with the key …
iPhosH-PseAAC: Identify phosphohistidine sites in proteins by blending statistical moments and position relative features according to the Chou's 5-step rule and …
Protein phosphorylation is one of the key mechanism in prokaryotes and eukaryotes and is
responsible for various biological functions such as protein degradation, intracellular …
responsible for various biological functions such as protein degradation, intracellular …
Optimization of serine phosphorylation prediction in proteins by comparing human engineered features and deep representations
Deep representations can be used to replace human-engineered representations, as such
features are constrained by certain limitations. For the prediction of protein post-translation …
features are constrained by certain limitations. For the prediction of protein post-translation …
Sequence-based identification of arginine amidation sites in proteins using deep representations of proteins and PseAAC
Background: Among all the major post-translational modifications, amidation seems to be a
small change, where a peptide ends with an amide group (-NH 2), not a carboxyl group …
small change, where a peptide ends with an amide group (-NH 2), not a carboxyl group …
iPhosS (Deep)-PseAAC: Identification of Phosphoserine Sites in Proteins Using Deep Learning on General Pseudo Amino Acid Compositions
Among all the PTMs, the protein phosphorylation is pivotal for various pathological and
physiological processes. About 30 percent of eukaryotic proteins undergo the …
physiological processes. About 30 percent of eukaryotic proteins undergo the …
ProtoPred: advancing oncological research through identification of proto-oncogene proteins
SJ Malebary, R Khan, YD Khan - IEEE Access, 2021 - ieeexplore.ieee.org
Proto-oncogenes are the genes that have the potential to transform normal cells into cancer
cells as a result of mutations. They usually contain encoding of proteins whose function is to …
cells as a result of mutations. They usually contain encoding of proteins whose function is to …
Sequence-based identification of allergen proteins developed by integration of PseAAC and statistical moments via 5-step rule
YD Khan, E Alzahrani, W Alghamdi… - Current …, 2020 - ingentaconnect.com
Background: Allergens are antigens that can stimulate an atopic type I human
hypersensitivity reaction by an immunoglobulin E (IgE) reaction. Some proteins are naturally …
hypersensitivity reaction by an immunoglobulin E (IgE) reaction. Some proteins are naturally …