Possible role of pineal and extra-pineal melatonin in surveillance, immunity, and first-line defense

RP Markus, KS Sousa… - International Journal of …, 2021 - mdpi.com
Melatonin is a highly conserved molecule found in prokaryotes and eukaryotes that acts as
the darkness hormone, translating environmental lighting to the whole body, and as a …

Immunoendocrinology and ecoimmunology in Brazilian anurans

FR Gomes, CB Madelaire, EH Moretti… - Integrative and …, 2022 - academic.oup.com
This paper reviews several aspects of immunoendocrinology and ecoimmunology in
Brazilian species of anurans under investigation for more than a decade, including (1) …

Immune and endocrine alterations at the early stage of inflammatory assemblage in toads after stimulation with heat-killed bacteria (Aeromonas hydrophila)

PGG Neto, SCM Titon, SM Muxel, B Titon Jr… - … and Physiology Part A …, 2024 - Elsevier
The red-leg syndrome in amphibians is a condition commonly associated with the bacteria
Aeromonas hydrophila and has led to population declines. However, there is little …

[HTML][HTML] Plasma steroids and immune measures vary with restraint duration in a toad (Rhinella icterica)

SCM Titon, BT Junior, AC De Figueiredo… - General and …, 2022 - Elsevier
Immunoenhancing effects have been widely described following acute stressors in several
vertebrates, and valuable contributions have been made from studies on acute stress to …

[HTML][HTML] Day vs. night variation in the LPS effects on toad's immunity and endocrine mediators

SCM Titon, B Titon Jr, SM Muxel… - … and Physiology Part A …, 2022 - Elsevier
The immune-endocrine interactions following an immune challenge have been
demonstrated in amphibians. When considering immune challenges, the immune-endocrine …

Time course of splenic cytokine mRNA and hormones during a lipopolysaccharide-induced inflammation in toads

FR Floreste, B Titon Jr, SCM Titon… - Integrative and …, 2022 - academic.oup.com
Inflammation comprises alterations in glucocorticoids (in amphibians, corticosterone—
CORT) and melatonin (MEL) levels, two hormones with immunomodulatory effects on …

Impacts of a Simulated Infection on the Locomotor Behavior of Invasive and Noninvasive Species of Congeneric Anurans

TG Oliveira, L Araspin, CA Navas… - Ecological and …, 2024 - journals.uchicago.edu
Locomotion is essential for survival, but it requires resources such as energy and
metabolites and therefore may conflict with other physiological processes that also demand …

Day Versus Night Melatonin and Corticosterone Modulation by LPS in Distinct Tissues of Toads (Rhinella Icterica)

JC Cyrino, AC de Figueiredo… - Integrative and …, 2022 - academic.oup.com
Pathogen-associated molecular patterns modulate melatonin (MEL) production in the pineal
and extra-pineal sites and corticosterone (CORT) synthesis in the adrenal/interrenal and …

Baseline and stress-induced changes in plasma bacterial killing ability against gram-negative bacteria are partially mediated by the complement system in Rhinella …

SA de Oliveira Rosa, BT Junior… - … and Physiology Part A …, 2024 - Elsevier
The plasma bacterial killing ability (BKA) is modulated by the stress response in vertebrates,
including amphibians. The complement system is an effector mechanism comprised of a set …

Immune-pineal-ocular Axis in Amphibians: Unveiling A Novel Connection

SCM Titon, PGG Neto, B Titon Jr… - Integrative and …, 2024 - academic.oup.com
Melatonin is a hormone known as an endogenous temporal marker signaling the dark
phase of the day. Although the eyes seem to be the main site of melatonin production in …