Environmental pollutants induce NLRP3 inflammasome activation and pyroptosis: roles and mechanisms in various diseases

Y Mou, W Liao, Y Liang, Y Li, M Zhao, Y Guo… - Science of The Total …, 2023 - Elsevier
Environmental pollution is changing with economic development. Most environmental
pollutants are characterized by stable chemical properties, strong migration, potential …

Dietary glucosinolates derived isothiocyanates: chemical properties, metabolism and their potential in prevention of Alzheimer's disease

F Khan, A Joshi, HP Devkota… - Frontiers in …, 2023 - frontiersin.org
Alzheimer's disease (AD) is the most prevalent form of dementia affecting millions of people
worldwide. It is a progressive, irreversible, and incurable neurodegenerative disorder that …

Stabilization of glutathione redox dynamics and CYP2E1 by green synthesized Moringa oleifera-mediated zinc oxide nanoparticles against acrylamide induced …

H Mahfouz, N Dahran, AAR Mohamed… - Food and Chemical …, 2023 - Elsevier
The terrible reality is that acrylamide (AA) is a common food contaminant found in a wide
variety of commonly consumed foods. This research involves the advancement of a more …

Bee venom (Apis mellifera L.) rescues zinc oxide nanoparticles induced neurobehavioral and neurotoxic impact via controlling neurofilament and GAP-43 in rat brain

NZH Eleiwa, MAA Ali, EN Said, MMM Metwally… - … Science and Pollution …, 2023 - Springer
This study investigated the possible beneficial role of the bee venom (BV, Apis mellifera L.)
against zinc oxide nanoparticles (ZNPs)-induced neurobehavioral and neurotoxic impacts in …

Green Synthesized Zinc Oxide Nanoparticles Attenuate Acrylamide-Induced Cardiac Injury via Controlling Endoplasmic Reticulum Stress–Associated Apoptosis …

M Alosaimi, YM Abd-Elhakim, AAR Mohamed… - … Trace Element Research, 2024 - Springer
Due to their distinctive properties, several eco-friendly metal oxide nanoparticles were
assessed for their possible cardioprotective properties. Acrylamide (ACD), a pervasive …

Thymol abates the detrimental impacts of imidacloprid on rat brains by lessening oxidative damage and apoptotic and inflammatory reactions

YM Abd-Elhakim, TM Saber, MMM Metwally… - Chemico-Biological …, 2023 - Elsevier
Imidacloprid (IMID) is one of the most widely used neonicotinoid insecticides globally and,
consequently, a probable widespread environmental contaminant. The potential neurotoxic …

Di (2-ethylhexyl) phthalate alters neurobehavioral responses and oxidative status, architecture, and GFAP and BDNF signaling in juvenile rat's brain: Protective role of …

NZH Eleiwa, ASF Elsayed, EN Said… - Food and Chemical …, 2024 - Elsevier
Abstract Di-(2-ethylhexyl) phthalate (DEHP), a phthalate plasticizer, is widely spread in the
environment, presenting hazards to human health and food safety. Hence, this study …

Luteolin/ZnO nanoparticles attenuate neuroinflammation associated with diabetes via regulating MicroRNA‐124 by targeting C/EBPA

EM Moustafa, FSM Moawed… - Environmental …, 2023 - Wiley Online Library
Objective The most prevalent brain‐specific microRNA, MicroRNA‐124, exhibits anti‐
inflammatory properties. Luteolin nano‐formulation with Zn oxide in the form of L/ZnO NPs …

Acrylamide-targeting renal miR− 21a− 5p/Fibrotic and miR122-5p/inflammatory signaling pathways and the role of a green approach for nano-zinc detected via in …

LS Alqahtani, ME Alosaimi… - Frontiers in …, 2024 - frontiersin.org
Introduction: Any disruption in renal function can have cascading effects on overall health.
Understanding how a heat-born toxicant like acrylamide (ACR) affects kidney tissue is vital …

Innovative strategies for overcoming blood-brain barrier challenges in Alzheimer's disease: A focus on green-synthesized metallic nanoparticles

K Nagori, KT Nakhate, K Yadav, A Thakur… - Inorganic Chemistry …, 2024 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder marked by cognitive
decline, memory loss, and behavioral instability. As the global population ages, the …