Oral squamous cell carcinoma (OSCC) is the most common type of oral cancer worldwide
and in the United States. OSCC remains a major cause of morbidity and mortality in patients …

Genetic variations along with epigenetic modifications of DNA are involved in colorectal
cancer (CRC) development and progression. CRC is the fourth leading cause of cancer …

Epidermal and hair follicle development from surface ectodermal progenitor cells requires
coordinated changes in gene expression. Histone deacetylases alter gene expression …

MYB is a leucine zipper transcription factor that is essential for hematopoesis and for
renewal of colonic crypts. There is also ample evidence showing that MYB is leukemogenic …

Abstract Water channel aquaporin 5 (AQP5) is highly expressed at the apical membrane of
alveolar type I epithelial cells and confers high osmotic water permeability. AQP5 is also …

Any alteration at the genetic or epigenetic level, may result in multiplex of diseases including
tumorigenesis which ultimately results in the cancer development. Restoration of the normal …

Potentiation of epidermal growth factor receptor (EGFR) inhibitors is required in squamous
cell carcinoma of head and neck (SCCHN) to improve their therapeutic index. We …

Histone acetylation marks have an important role in controlling gene expression and are
removed by histone deacetylases (HDACs). These marks are read by bromodomain and …

Mushrooms are an integral part of Traditional Chinese Medicine (TCM), and have been
used for millennia to prevent or treat a variety of diseases. Currently mushrooms or their …

Survivin, an anti-apoptotic molecule abundantly expressed in most human neoplasms, has
been reported to contribute to cancer initiation and drug resistance in a wide variety of …