[HTML][HTML] Laboratory testing in patients treated with direct oral anticoagulants: a practical guide for clinicians

J Douxfils, W Ageno, CM Samama, S Lessire… - Journal of Thrombosis …, 2018 - Elsevier
Click to hear Dr Baglin's perspective on the role of the laboratory in treatment with new oral
anticoagulants Summary One of the key benefits of the direct oral anticoagulants (DOACs) is …

2021 update of the International Council for Standardization in Haematology recommendations for laboratory measurement of direct oral anticoagulants

J Douxfils, DM Adcock, SM Bates… - Thrombosis and …, 2021 - thieme-connect.com
In 2018, the International Council for Standardization in Haematology (ICSH) published a
consensus document providing guidance for laboratories on measuring direct oral …

The European guideline on management of major bleeding and coagulopathy following trauma

DR Spahn, B Bouillon, V Cerny, J Duranteau… - Critical care, 2019 - Springer
Background Severe traumatic injury continues to present challenges to healthcare systems
around the world, and post-traumatic bleeding remains a leading cause of potentially …

International Council for Standardization in Haematology (ICSH) recommendations for laboratory measurement of direct oral anticoagulants

RC Gosselin, DM Adcock, SM Bates… - Thrombosis and …, 2018 - thieme-connect.com
This guidance document was prepared on behalf of the International Council for
Standardization in Haematology (ICSH) for providing haemostasis-related guidance …

The impact of direct oral anticoagulants on viscoelastic testing–A systematic review

SD Sahli, C Castellucci, TR Roche, J Rössler… - Frontiers in …, 2022 - frontiersin.org
Background In case of bleeding patients and in acute care, the assessment of residual direct
oral anticoagulant (DOAC) activity is essential for evaluating the potential impact on …

Point-of-care diagnostics in coagulation management

SD Sahli, J Rössler, DW Tscholl, JD Studt, DR Spahn… - Sensors, 2020 - mdpi.com
This review provides a comprehensive and up-to-date overview of point-of-care (POC)
devices most commonly used for coagulation analyses in the acute settings. Fast and …

“In less than no time”: feasibility of rotational thromboelastometry to detect anticoagulant drugs activity and to guide reversal therapy

V Pavoni, L Gianesello, D Conti, P Ballo… - Journal of Clinical …, 2022 - mdpi.com
Anticoagulant drugs (ie, unfractionated heparin, low-molecular-weight heparins, vitamin K
antagonists, and direct oral anticoagulants) are widely employed in preventing and treating …

Impact of four direct oral anticoagulants on rotational thromboelastometry (ROTEM)

L Seyve, C Richarme, B Polack… - International Journal of …, 2018 - Wiley Online Library
Abstract Introduction Rotational Thromboelastometry (ROTEM) is a point of care method
used to monitor coagulation during surgery and to guide transfusion strategies in patients …

A universal anti‐Xa assay for rivaroxaban, apixaban, and edoxaban measurements: method validation, diagnostic accuracy and external validation

G Willekens, JD Studt, A Mendez… - British journal of …, 2021 - Wiley Online Library
A universal anti‐Xa assay for the determination of rivaroxaban, apixaban and edoxaban
drug concentrations would simplify laboratory procedures and facilitate widespread …

Automated thrombin generation assay for rivaroxaban, apixaban, and edoxaban measurements

T Meihandoest, JD Studt, A Mendez… - Frontiers in …, 2021 - frontiersin.org
Background: The thrombin generation assay (TG) is a promising approach to measure the
degree of anticoagulation in patients treated with direct oral anticoagulants (DOAC). A …