Biochemistry of peroxynitrite and protein tyrosine nitration

G Ferrer-Sueta, N Campolo, M Trujillo… - Chemical …, 2018 - ACS Publications
Peroxynitrite is a short-lived and reactive biological oxidant formed from the diffusion-
controlled reaction of the free radicals superoxide (O2•–) and nitric oxide (• NO). In this …

Nitric oxide in macrophage immunometabolism: hiding in plain sight

EM Palmieri, C McGinity, DA Wink, DW McVicar - Metabolites, 2020 - mdpi.com
Nitric Oxide (NO) is a soluble endogenous gas with various biological functions like
signaling, and working as an effector molecule or metabolic regulator. In response to …

N-Acetylcysteine (NAC): Impacts on Human Health

MCS Tenório, NG Graciliano, FA Moura, ACM Oliveira… - Antioxidants, 2021 - mdpi.com
N-acetylcysteine (NAC) is a medicine widely used to treat paracetamol overdose and as a
mucolytic compound. It has a well-established safety profile, and its toxicity is uncommon …

The chemistry and biological activities of N-acetylcysteine

Y Samuni, S Goldstein, OM Dean, M Berk - Biochimica et Biophysica Acta …, 2013 - Elsevier
BACKGROUND: N-acetylcysteine (NAC) has been in clinical practice for several decades. It
has been used as a mucolytic agent and for the treatment of numerous disorders including …

Recent progress in the development of fluorescent, luminescent and colorimetric probes for detection of reactive oxygen and nitrogen species

X Chen, F Wang, JY Hyun, T Wei, J Qiang… - Chemical Society …, 2016 - pubs.rsc.org
Reactive oxygen (ROS) and nitrogen (RNS) species cause oxidative and nitrosative
stresses, respectively. These stresses are implicated not only in diverse physiological …

Nitrosopumilus maritimus genome reveals unique mechanisms for nitrification and autotrophy in globally distributed marine crenarchaea

CB Walker, JR de la Torre, MG Klotz… - Proceedings of the …, 2010 - National Acad Sciences
Ammonia-oxidizing archaea are ubiquitous in marine and terrestrial environments and now
thought to be significant contributors to carbon and nitrogen cycling. The isolation of …

[图书][B] Algal physiology and large-scale outdoor cultures of microalgae

MA Borowitzka - 2016 - Springer
The reliable and efficient production of microalgae in large-scale commercial culture,
whether in open ponds or in closed photobioreactors, requires a good understanding of the …

Biological activities and potential oral applications of N‐acetylcysteine: progress and prospects

Y Pei, H Liu, Y Yang, Y Yang, Y Jiao… - Oxidative medicine …, 2018 - Wiley Online Library
N‐Acetylcysteine (NAC), a cysteine prodrug and glutathione (GSH) precursor, has been
used for several decades in clinical therapeutic practices as a mucolytic agent and for the …

Detection and quantification of nitric oxide–derived oxidants in biological systems

MN Möller, N Rios, M Trujillo, R Radi… - Journal of biological …, 2019 - ASBMB
The free radical nitric oxide (NO•) exerts biological effects through the direct and reversible
interaction with specific targets (eg soluble guanylate cyclase) or through the generation of …

The chemistry of nitroxyl (HNO) and implications in biology

KM Miranda - Coordination Chemistry Reviews, 2005 - Elsevier
Over the past century, HNO research has evolved from fundamental physical examinations
to elucidation of interactions in atmospheric, industrial and bacterial processes. Most …