Applications of Raman spectroscopy in cancer diagnosis
Novel approaches toward understanding the evolution of disease can lead to the discovery
of biomarkers that will enable better management of disease progression and improve …
of biomarkers that will enable better management of disease progression and improve …
Raman spectroscopy and imaging for cancer diagnosis
S Cui, S Zhang, S Yue - Journal of healthcare engineering, 2018 - Wiley Online Library
Raman scattering has long been used to analyze chemical compositions in biological
systems. Owing to its high chemical specificity and noninvasive detection capability, Raman …
systems. Owing to its high chemical specificity and noninvasive detection capability, Raman …
Artificial-intelligence-based molecular classification of diffuse gliomas using rapid, label-free optical imaging
Molecular classification has transformed the management of brain tumors by enabling more
accurate prognostication and personalized treatment. However, timely molecular diagnostic …
accurate prognostication and personalized treatment. However, timely molecular diagnostic …
Near real-time intraoperative brain tumor diagnosis using stimulated Raman histology and deep neural networks
Intraoperative diagnosis is essential for providing safe and effective care during cancer
surgery. The existing workflow for intraoperative diagnosis based on hematoxylin and eosin …
surgery. The existing workflow for intraoperative diagnosis based on hematoxylin and eosin …
Virtual formalin-fixed and paraffin-embedded staining of fresh brain tissue via stimulated Raman CycleGAN model
Intraoperative histology is essential for surgical guidance and decision-making. However,
frozen-sectioned hematoxylin and eosin (H&E) staining suffers from degraded accuracy …
frozen-sectioned hematoxylin and eosin (H&E) staining suffers from degraded accuracy …
Instant diagnosis of gastroscopic biopsy via deep-learned single-shot femtosecond stimulated Raman histology
Gastroscopic biopsy provides the only effective method for gastric cancer diagnosis, but the
gold standard histopathology is time-consuming and incompatible with gastroscopy …
gold standard histopathology is time-consuming and incompatible with gastroscopy …
Stimulated Raman scattering microscopy enables gleason scoring of prostate core needle biopsy by a convolutional neural network
Focal therapy (FT) has been proposed as an approach to eradicate clinically significant
prostate cancer while preserving the normal surrounding tissues to minimize treatment …
prostate cancer while preserving the normal surrounding tissues to minimize treatment …
[HTML][HTML] Rapid histology of laryngeal squamous cell carcinoma with deep-learning based stimulated Raman scattering microscopy
L Zhang, Y Wu, B Zheng, L Su, Y Chen, S Ma, Q Hu… - Theranostics, 2019 - ncbi.nlm.nih.gov
Maximal resection of tumor while preserving the adjacent healthy tissue is particularly
important for larynx surgery, hence precise and rapid intraoperative histology of laryngeal …
important for larynx surgery, hence precise and rapid intraoperative histology of laryngeal …
Rapid unperturbed‐tissue analysis for intraoperative cancer diagnosis using an enzyme‐activated NIR‐II nanoprobe
Y Zhan, S Ling, H Huang, Y Zhang… - Angewandte Chemie …, 2021 - Wiley Online Library
Accurate intraoperative tissue identification is critical to tumor surgery. However,
conventional methods are labor‐and time‐intensive, which greatly delay the intraoperative …
conventional methods are labor‐and time‐intensive, which greatly delay the intraoperative …
Localization of protoporphyrin IX during glioma-resection surgery via paired stimulated Raman histology and fluorescence microscopy
M Nasir-Moin, LI Wadiura, V Sacalean… - Nature biomedical …, 2024 - nature.com
The most widely used fluorophore in glioma-resection surgery, 5-aminolevulinic acid (5-
ALA), is thought to cause the selective accumulation of fluorescent protoporphyrin IX (PpIX) …
ALA), is thought to cause the selective accumulation of fluorescent protoporphyrin IX (PpIX) …