Fruit and vegetable polyphenols as natural bioactive inhibitors of pancreatic lipase and cholesterol esterase: Inhibition mechanisms, polyphenol influences …

X He, L Chen, Y Pu, H Wang, J Cao, W Jiang - Food Bioscience, 2023 - Elsevier
Pancreatic lipase and cholesterol esterase are key enzymes in the lipid digestion and
absorption pathway and are also targeted for control in response to obesity and other …

[HTML][HTML] Structure–activity relationships and changes in the inhibition of xanthine oxidase by polyphenols: A Review

K Li, Y Wang, W Liu, C Zhang, Y Xi, Y Zhou, H Li, X Liu - Foods, 2024 - mdpi.com
Hyperuricemia (HUA), or elevated uric acid in the blood, has become more prevalent in
recent years. Polyphenols, which are known to have good inhibitory activity on xanthine …

Exploring synergistic inhibitory mechanisms of flavonoid mixtures on α-glucosidase by experimental analysis and molecular dynamics simulation

J Pan, M Nawaz, J Liu, H Liu, Z Lv, W Yang, Z Jiao… - Food Chemistry, 2025 - Elsevier
The study was the first to evaluate the synergistic interaction of luteolin+ quercetin, luteolin+
3-O-methylquercetin, and quercetin+ 3-O-methylquercetin mixtures on α-glucosidase and …

Inhibitory potential of α-amylase, α-glucosidase, and pancreatic lipase by a formulation of five plant extracts: TOTUM-63

Q Haguet, F Le Joubioux, V Chavanelle… - International Journal of …, 2023 - mdpi.com
Controlling post-prandial hyperglycemia and hyperlipidemia, particularly by regulating the
activity of digestive enzymes, allows managing type 2 diabetes and obesity. The aim of this …

Characterization of the synergistic antioxidant activity of epigallocatechin gallate (EGCG) and kaempferol

Q Zhang, J Pan, H Liu, Z Jiao - Molecules, 2023 - mdpi.com
Epigallocatechin gallate (EGCG) and kaempferol exhibit cellular antioxidant activity;
however, their interactive effects in terms of antioxidant actions and underlying mechanisms …

Anti-Hyperglycemic Effects of Bioactive Compounds in the Context of the Prevention of Diet-Related Diseases

R Alfahel, T Sawicki, M Jabłońska, KE Przybyłowicz - Foods, 2023 - mdpi.com
Diet-related diseases are health conditions primary caused by poor nutrition. These
diseases encompass obesity, type 2 diabetes, cardiovascular diseases, osteoporosis, and …

[HTML][HTML] Enhanced bioactive component recovery from Sohiong via optimized enzyme-assisted microwave extraction and its stability in freeze-dried premix

R Sasikumar, R Nongmaithem, K Vivek, S Janghu… - LWT, 2024 - Elsevier
In the process of juice preparation, a significant portion of bioactive constituents remains
unextracted, leading to wastage and reduced nutritional value. In this study, an Enzyme …

[HTML][HTML] Discovery of Curcuminoids as Pancreatic Lipase Inhibitors from Medicine-and-Food Homology Plants

XQ He, HD Zou, Y Liu, XJ Chen, AG Atanasov… - Nutrients, 2024 - mdpi.com
Researchers are increasingly interested in discovering new pancreatic lipase inhibitors as
anti-obesity ingredients. Medicine-and-food homology plants contain a diverse set of natural …

A Review of the Role of an Anthocyanin, Cyanidin-3-O-β-glucoside in Obesity-Related Complications

P Deepa, M Hong, K Sowndhararajan, S Kim - Plants, 2023 - mdpi.com
Obesity has become a major health issue worldwide and obese individuals possess higher
levels of adipose tissue when compared with healthy individuals. Obesity is highly …

Methodologies for assessing pancreatic lipase catalytic activity: a review

S Rocha, AT Rufino, M Freitas, AMS Silva… - Critical Reviews in …, 2024 - Taylor & Francis
Obesity is a disease of epidemic proportions with a concerning increasing trend. Regarded
as one of the main sources of energy, lipids can also represent a big part of an unnecessary …