Antimicrobial resistance to virtually all clinically applied antibiotic classes severely limits the
available options to treat bacterial infections. Hence, there is an urgent need to develop and …

Bacillus subtilis is the best described member of the Gram positive bacteria. It is a typical rod
shaped bacterium and grows by elongation in its long axis, before dividing at mid cell to …

The mechanism by which bacteria divide is not well understood. Cell division is mediated by
filaments of FtsZ and FtsA (FtsAZ) that recruit septal peptidoglycan-synthesizing enzymes to …

Bacterial cell division requires recruitment of peptidoglycan (PG) synthases to the division
site by the tubulin homologue, FtsZ. Septal PG synthases promote septum growth. FtsZ …

Combating anti-microbial resistance by developing alternative strategies is the need of the
hour. Cell division, particularly FtsZ, is being extensively studied for its potential as an …

FtsZ is a self-assembling GTPase that forms, below the inner membrane, the mid-cell Z-ring
guiding bacterial division. FtsZ monomers polymerize head to tail forming tubulin-like …

Bacterial cell division is mediated by the tubulin-homolog FtsZ, which recruits peptidoglycan
(PG) synthesis enzymes to the division site. Septal PG synthases promote inward growth of …

Bacterial cell division is a highly controlled process regulated accurately by a diverse array
of proteins spatially and temporally working together. Among these proteins, FtsZ is …

FtsZ is an essential and central protein for cell division in most bacteria. Because of its ability
to organize into dynamic polymers at the cell membrane and recruit other protein partners to …

The interaction of MinC with FtsZ and its effects on FtsZ polymerization were studied under
close to physiological conditions by a combination of biophysical methods. The Min system …