Role of vitamin D deficiency in the pathogenesis of cardiovascular and cerebrovascular diseases

É Pál, Z Ungvári, Z Benyó, S Várbíró - Nutrients, 2023 - mdpi.com
Deficiency in vitamin D (VitD), a lipid-soluble vitamin and steroid hormone, affects
approximately 24% to 40% of the population of the Western world. In addition to its well …

Ultra-slow oscillations in fMRI and resting-state connectivity: neuronal and vascular contributions and technical confounds

PJ Drew, C Mateo, KL Turner, X Yu, D Kleinfeld - Neuron, 2020 - cell.com
Summary Ultra-slow,∼ 0.1-Hz variations in the oxygenation level of brain blood are widely
used as an fMRI-based surrogate of" resting-state" neuronal activity. The temporal …

Neurovascular coupling is optimized to compensate for the increase in proton production from nonoxidative glycolysis and glycogenolysis during brain activation and maintain homeostasis of pH, p …

M DiNuzzo, GA Dienel, KL Behar… - Journal of …, 2024 - Wiley Online Library
During transient brain activation cerebral blood flow (CBF) increases substantially more than
cerebral metabolic rate of oxygen consumption (CMRO2) resulting in blood …

Aerobic exercise reverses aging-induced depth-dependent decline in cerebral microcirculation

P Shin, Q Pian, H Ishikawa, G Hamanaka… - Elife, 2023 - elifesciences.org
Aging is a major risk factor for cognitive impairment. Aerobic exercise benefits brain function
and may promote cognitive health in older adults. However, underlying biological …

Awake mouse brain photoacoustic and optical imaging through a transparent ultrasound cranial window

S Mirg, H Chen, KL Turner, KW Gheres, J Liu… - Optics Letters, 2022 - opg.optica.org
Optical resolution photoacoustic microscopy (OR-PAM) can map the cerebral vasculature at
capillary-level resolution. However, the OR-PAM setup's bulky imaging head makes awake …

Intrinsic, widefield optical imaging of hemodynamics in rodent models of Alzheimer's disease and neurological injury

C Crouzet, T Phan, RH Wilson, TJ Shin… - …, 2023 - spiedigitallibrary.org
The complex cerebrovascular network is critical to controlling local cerebral blood flow
(CBF) and maintaining brain homeostasis. Alzheimer's disease (AD) and neurological injury …

Wide-field optical imaging in mouse models of ischemic stroke

JA Padawer-Curry, RM Bowen, A Jarang… - Neural Repair: Methods …, 2023 - Springer
Functional neuroimaging is a powerful tool for evaluating how local and global brain circuits
evolve after focal ischemia and how these changes relate to functional recovery. For …

Quantitative Optical Imaging of Oxygen in Brain Vasculature

E Rathbone, D Fu - The Journal of Physical Chemistry B, 2024 - ACS Publications
The intimate relationship between neuronal activity and cerebral oxygenation underpins
fundamental brain functions like cognition, sensation, and motor control. Optical imaging …

The inhibitory influence of carvacrol on behavioral modifications, brain oxidation, and general inflammation triggered by paraquat exposure through inhalation

R Khosravi, S Beigoli, S Behrouz, S Amirahmadi… - NeuroToxicology, 2024 - Elsevier
The current study investigated how carvacrol (C) can prevent behavioral and brain oxidative
changes, along with systemic inflammation caused by inhaled paraquat (PQ). Control rats …

Origins of 1/f-like tissue oxygenation fluctuations in the murine cortex

Q Zhang, KW Gheres, PJ Drew - PLoS biology, 2021 - journals.plos.org
The concentration of oxygen in the brain spontaneously fluctuates, and the distribution of
power in these fluctuations has a 1/f-like spectra, where the power present at low …