Systemic lupus erythematosus-complicating immune thrombocytopenia: from pathogenesis to treatment

Y Jiang, Y Cheng, S Ma, T Li, Z Chen, X Zuo… - Journal of …, 2022 - Elsevier
Immune thrombocytopenia (ITP) is a common hematological manifestation of systemic lupus
erythematosus (SLE). The heterogeneity of its clinical characteristics and therapeutic …

[HTML][HTML] Platelet intrinsic apoptosis

EC Josefsson - Thrombosis Research, 2023 - Elsevier
In a healthy individual, the lifespan of most platelets is tightly regulated by intrinsic, or
mitochondrial, apoptosis. This is a special form of programmed cell death governed by the …

Desialylation by neuraminidases in platelets, kiss of death or bittersweet?

N Butta, DE van der Wal - Current Opinion in Hematology, 2025 - journals.lww.com
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Thrombocytopenia in Klebsiella pneumoniae liver abscess: a retrospective study on its correlation with disease severity and potential causes

L Chen, H Wang, H Wang, Y Guo… - Frontiers in Cellular and …, 2024 - frontiersin.org
Objective Thrombocytopenia is commonly associated with infectious diseases and serves as
an indicator of disease severity. However, reports on its manifestation in conjunction with …

[HTML][HTML] Placental glycosylation senses the anti-angiogenic milieu induced by human sFLT1 during pregnancy

K Kirkgöz, R Vogtmann, Y Xie, F Zhao, A Riedel… - Journal of Reproductive …, 2024 - Elsevier
Abnormal placental angiogenesis during gestation resulting from high levels of anti-
angiogenic factors, soluble fms-like tyrosine kinase-1 (sFLT1) and soluble endoglin, has …

NANS‐CDG: Expanding clinical insights with a novel patient with novel variants

S Yoo, CK Cheon - American Journal of Medical Genetics Part …, 2024 - Wiley Online Library
N‐acetyl‐d‐neuraminic acid synthase‐congenital disorder of glycosylation (NANS‐CDG) is
a rare autosomal recessive defect in the N‐acetyl‐neuraminic acid biosynthesis pathway …

Desialylation unmasks HPA-9B alloantibodies

MT Ahlen, JB Bussel - Blood, 2023 - ashpublications.org
In this issue of Blood, Zhang et al 1 report new insight into the role of sialyation of
glycoprotein (GP) IIb for the detection of maternal alloantibodies (to human platelet antigen …

Pathophysiologie und Diagnostik der Immunthrombozytopenie

A Giagounidis - DMW-Deutsche Medizinische Wochenschrift, 2024 - thieme-connect.com
Die Immunthrombozytopenie (ITP) entsteht durch Autoantikörper-Bildung gegen
Oberflächenantigene der Blutplättchen. Die Erkrankung tritt als primäre ITP ohne …

Mechanisms of dengue virus-mediated thrombocytopenia through virus-encoded protein synthesis and induction of selective host proteins in megakaryocytes and …

TZ Tegegn - 2024 - open.library.ubc.ca
Abstract According to the World Health Organization, approximately 50% of the world's
population lives in regions where dengue virus (DENV) is endemic. Each year, about 400 …

Defining mechanisms of binding utilized by the infective endocarditis pathogen Streptococcus mitis

A Narayana - 2024 - kb.osu.edu
Streptococcus mitis is an oral commensal and a common cause of subacute infective
endocarditis (IE), a bacterial infection exhibiting an upward trend in mortality and …